<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2022 Workiva-->
<!--r:2773cc2b-7980-410d-a1ba-8699b4858d8e,g:286ee192-dded-42f4-bbdd-1c8bc6636195-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedBalanceSheets" xlink:type="simple" xlink:href="dbx-20220630.xsd#CondensedConsolidatedBalanceSheets"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_e0d88ea4-a5dd-422c-a081-5ef652bc486f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_9a06138e-d293-48d5-bfe3-3bea2487482b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e0d88ea4-a5dd-422c-a081-5ef652bc486f" xlink:to="loc_us-gaap_LiabilitiesCurrent_9a06138e-d293-48d5-bfe3-3bea2487482b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_e5b57dc1-003f-47fa-a65e-9f2f2ff5b61e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e0d88ea4-a5dd-422c-a081-5ef652bc486f" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_e5b57dc1-003f-47fa-a65e-9f2f2ff5b61e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_596d20bf-e1f6-42f0-aeb6-67f23d959804" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e0d88ea4-a5dd-422c-a081-5ef652bc486f" xlink:to="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_596d20bf-e1f6-42f0-aeb6-67f23d959804" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_a29620fc-96da-4511-a3c5-57aaebaf65cc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e0d88ea4-a5dd-422c-a081-5ef652bc486f" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_a29620fc-96da-4511-a3c5-57aaebaf65cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtNoncurrent_ce0540d7-f285-41c9-b8d7-78e87b59ce90" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ConvertibleDebtNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_e0d88ea4-a5dd-422c-a081-5ef652bc486f" xlink:to="loc_us-gaap_ConvertibleDebtNoncurrent_ce0540d7-f285-41c9-b8d7-78e87b59ce90" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_49e81bb6-96be-4603-8e6e-adccf8f7c1f6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_5d55ac4b-930d-4e54-8d11-1e9d94c2ce84" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_49e81bb6-96be-4603-8e6e-adccf8f7c1f6" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_5d55ac4b-930d-4e54-8d11-1e9d94c2ce84" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_fbbb1a50-bbb1-44e1-af8d-5573c156db17" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_49e81bb6-96be-4603-8e6e-adccf8f7c1f6" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_fbbb1a50-bbb1-44e1-af8d-5573c156db17" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_30437cb0-bf98-41dd-80e4-e5fc9e8c1cc1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_49e81bb6-96be-4603-8e6e-adccf8f7c1f6" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_30437cb0-bf98-41dd-80e4-e5fc9e8c1cc1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_ec2183e9-c205-4c71-bb36-4c45b952895d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_49e81bb6-96be-4603-8e6e-adccf8f7c1f6" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_ec2183e9-c205-4c71-bb36-4c45b952895d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_72b3ea66-84ba-45d7-8ffe-44f683233b26" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_f4263bad-7312-4e92-ab02-089391d21c4a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_72b3ea66-84ba-45d7-8ffe-44f683233b26" xlink:to="loc_us-gaap_AccountsPayableCurrent_f4263bad-7312-4e92-ab02-089391d21c4a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_c7540b0a-f590-490c-a215-872e71e3fc5b" xlink:href="dbx-20220630.xsd#dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_72b3ea66-84ba-45d7-8ffe-44f683233b26" xlink:to="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_c7540b0a-f590-490c-a215-872e71e3fc5b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_e7a2500b-58e2-46c9-938a-a9adfd809b52" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_72b3ea66-84ba-45d7-8ffe-44f683233b26" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_e7a2500b-58e2-46c9-938a-a9adfd809b52" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_97c1470b-07da-43da-8b41-6e40a1bf1892" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_72b3ea66-84ba-45d7-8ffe-44f683233b26" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_97c1470b-07da-43da-8b41-6e40a1bf1892" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityCurrent_ce2cc2f1-9662-478a-aade-39a5b14b5893" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_72b3ea66-84ba-45d7-8ffe-44f683233b26" xlink:to="loc_us-gaap_FinanceLeaseLiabilityCurrent_ce2cc2f1-9662-478a-aade-39a5b14b5893" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_cea5d558-2317-471f-b101-47a534c867df" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_72b3ea66-84ba-45d7-8ffe-44f683233b26" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_cea5d558-2317-471f-b101-47a534c867df" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_78c2068a-0393-420c-a771-156c43e771f9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_1df8d2ed-da92-4515-b911-a301dfba91d0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_78c2068a-0393-420c-a771-156c43e771f9" xlink:to="loc_us-gaap_AdditionalPaidInCapital_1df8d2ed-da92-4515-b911-a301dfba91d0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_ef7d77e5-b1d6-41cc-af2f-210d9a432508" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_78c2068a-0393-420c-a771-156c43e771f9" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_ef7d77e5-b1d6-41cc-af2f-210d9a432508" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_7ab60c8d-862f-4fe7-b522-d740640fc947" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_78c2068a-0393-420c-a771-156c43e771f9" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_7ab60c8d-862f-4fe7-b522-d740640fc947" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_5612e4de-6003-46be-93fc-9eef9121f920" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_3cf45c7c-4181-4f81-9d41-4a7ebfe344b9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_5612e4de-6003-46be-93fc-9eef9121f920" xlink:to="loc_us-gaap_StockholdersEquity_3cf45c7c-4181-4f81-9d41-4a7ebfe344b9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_e677ea73-26e2-409b-989a-a348f179eb1d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Liabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_5612e4de-6003-46be-93fc-9eef9121f920" xlink:to="loc_us-gaap_Liabilities_e677ea73-26e2-409b-989a-a348f179eb1d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_9d34d47c-a7d7-4d74-8c74-28d7c2d77a71" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_5612e4de-6003-46be-93fc-9eef9121f920" xlink:to="loc_us-gaap_CommitmentsAndContingencies_9d34d47c-a7d7-4d74-8c74-28d7c2d77a71" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_a704028b-ac3f-482b-8179-93c5f73bf781" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_3a22a178-3086-437a-9872-b9b536c87469" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_a704028b-ac3f-482b-8179-93c5f73bf781" xlink:to="loc_us-gaap_AssetsCurrent_3a22a178-3086-437a-9872-b9b536c87469" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_3d77dfda-c9ac-49e4-ad5f-bf707c03cce3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_a704028b-ac3f-482b-8179-93c5f73bf781" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_3d77dfda-c9ac-49e4-ad5f-bf707c03cce3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_3c9e9404-ff42-47a6-bdfa-067c357f0e26" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_a704028b-ac3f-482b-8179-93c5f73bf781" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_3c9e9404-ff42-47a6-bdfa-067c357f0e26" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_5ba0f866-4237-43c2-90e3-5cd1d17a910d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_a704028b-ac3f-482b-8179-93c5f73bf781" xlink:to="loc_us-gaap_Goodwill_5ba0f866-4237-43c2-90e3-5cd1d17a910d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_ff890383-d526-43b2-af30-71ca6dd117a0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_a704028b-ac3f-482b-8179-93c5f73bf781" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_ff890383-d526-43b2-af30-71ca6dd117a0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_96492b95-2ce3-4d26-9b0e-9b15adb45aba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_a704028b-ac3f-482b-8179-93c5f73bf781" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_96492b95-2ce3-4d26-9b0e-9b15adb45aba" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedStatementsofOperations" xlink:type="simple" xlink:href="dbx-20220630.xsd#CondensedConsolidatedStatementsofOperations"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedStatementsofOperations" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_3c8fe6f6-bab0-46af-a080-4c5ce742f69b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_83d7a38f-cb60-4022-bf3d-03b6f5b035c5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_3c8fe6f6-bab0-46af-a080-4c5ce742f69b" xlink:to="loc_us-gaap_OperatingIncomeLoss_83d7a38f-cb60-4022-bf3d-03b6f5b035c5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_7a734bb6-33f5-4931-b082-e641b8e04ef5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestIncomeExpenseNonoperatingNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_3c8fe6f6-bab0-46af-a080-4c5ce742f69b" xlink:to="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_7a734bb6-33f5-4931-b082-e641b8e04ef5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_8e63e82d-85f3-4688-9037-bb98391e5901" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_3c8fe6f6-bab0-46af-a080-4c5ce742f69b" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_8e63e82d-85f3-4688-9037-bb98391e5901" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_99a4bc60-fead-486a-8abc-c8c226813394" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GrossProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_74903eb5-79a4-454e-93d0-34da7e3dccd8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_99a4bc60-fead-486a-8abc-c8c226813394" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_74903eb5-79a4-454e-93d0-34da7e3dccd8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_6d4c29a5-b10e-44b0-b096-08a84e7cf12e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_99a4bc60-fead-486a-8abc-c8c226813394" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_6d4c29a5-b10e-44b0-b096-08a84e7cf12e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_daa0202c-43d6-464b-b78d-80769c9372db" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingAndMarketingExpense_4c604fdd-7418-4d23-96de-a8c40b75cd1b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SellingAndMarketingExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_daa0202c-43d6-464b-b78d-80769c9372db" xlink:to="loc_us-gaap_SellingAndMarketingExpense_4c604fdd-7418-4d23-96de-a8c40b75cd1b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_513eee3e-736b-4d41-90db-0a8079edbae9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_daa0202c-43d6-464b-b78d-80769c9372db" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_513eee3e-736b-4d41-90db-0a8079edbae9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_3d8fcce7-f996-42ce-9641-2d8e361a141b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_daa0202c-43d6-464b-b78d-80769c9372db" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_3d8fcce7-f996-42ce-9641-2d8e361a141b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairmentOfRealEstate_c160377a-442b-4f4b-a2fb-efdedb538b65" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ImpairmentOfRealEstate"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_daa0202c-43d6-464b-b78d-80769c9372db" xlink:to="loc_us-gaap_ImpairmentOfRealEstate_c160377a-442b-4f4b-a2fb-efdedb538b65" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_99768013-c789-4cf2-ba6a-9739d4b3321e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_c52f11a0-ae01-4a5e-ad72-d704c8537f2f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_99768013-c789-4cf2-ba6a-9739d4b3321e" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_c52f11a0-ae01-4a5e-ad72-d704c8537f2f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_0ee8b621-2c13-4363-8870-d0de8fd0d9f5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_99768013-c789-4cf2-ba6a-9739d4b3321e" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_0ee8b621-2c13-4363-8870-d0de8fd0d9f5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_b72e213f-758a-4f4e-bc0b-48fd14bb6618" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_b3f8851e-a88b-4ca7-a437-f8283a01dcec" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingExpenses"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_b72e213f-758a-4f4e-bc0b-48fd14bb6618" xlink:to="loc_us-gaap_OperatingExpenses_b3f8851e-a88b-4ca7-a437-f8283a01dcec" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_1ec9f4a5-7b5b-4f5f-90d9-9cffd11b742b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GrossProfit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_b72e213f-758a-4f4e-bc0b-48fd14bb6618" xlink:to="loc_us-gaap_GrossProfit_1ec9f4a5-7b5b-4f5f-90d9-9cffd11b742b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedStatementsofComprehensiveIncome" xlink:type="simple" xlink:href="dbx-20220630.xsd#CondensedConsolidatedStatementsofComprehensiveIncome"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedStatementsofComprehensiveIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_f5b88fe3-5901-4a76-8145-b1c08b5c3e57" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_4be0cab5-e8e6-4c38-b147-3906d030d56f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_f5b88fe3-5901-4a76-8145-b1c08b5c3e57" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_4be0cab5-e8e6-4c38-b147-3906d030d56f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_f418ac71-f05d-49c9-9887-3a19bfcfa2af" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_f5b88fe3-5901-4a76-8145-b1c08b5c3e57" xlink:to="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_f418ac71-f05d-49c9-9887-3a19bfcfa2af" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_f1e1d2b6-ef14-41a4-9f43-ad632c681c41" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_e2fbdf75-1836-499b-9fe4-ca001d2b0816" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_f1e1d2b6-ef14-41a4-9f43-ad632c681c41" xlink:to="loc_us-gaap_NetIncomeLoss_e2fbdf75-1836-499b-9fe4-ca001d2b0816" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_b54d1de6-e6c7-4855-9c64-186fd4720e5d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_f1e1d2b6-ef14-41a4-9f43-ad632c681c41" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_b54d1de6-e6c7-4855-9c64-186fd4720e5d" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="dbx-20220630.xsd#CondensedConsolidatedStatementsofCashFlows"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_fff2e7a8-d344-4b9a-802e-80e9b904ce23" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_05b9405a-a131-4c1f-ab1e-4d1970684d2a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_fff2e7a8-d344-4b9a-802e-80e9b904ce23" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_05b9405a-a131-4c1f-ab1e-4d1970684d2a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_e915e7cc-176b-49ef-8e47-d0bc100bdb47" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_fff2e7a8-d344-4b9a-802e-80e9b904ce23" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_e915e7cc-176b-49ef-8e47-d0bc100bdb47" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_c513b05c-357b-4098-ae09-779443075e01" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_fff2e7a8-d344-4b9a-802e-80e9b904ce23" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_c513b05c-357b-4098-ae09-779443075e01" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_7e8891ed-bbc9-4468-920e-e07396fd33d7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_fff2e7a8-d344-4b9a-802e-80e9b904ce23" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_7e8891ed-bbc9-4468-920e-e07396fd33d7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments_850fca39-b997-403e-8b95-e00f3f4ca233" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_fff2e7a8-d344-4b9a-802e-80e9b904ce23" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments_850fca39-b997-403e-8b95-e00f3f4ca233" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfShortTermInvestments_152e5abe-e4d6-4adb-92c4-c26c220eb297" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromSaleOfShortTermInvestments"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_fff2e7a8-d344-4b9a-802e-80e9b904ce23" xlink:to="loc_us-gaap_ProceedsFromSaleOfShortTermInvestments_152e5abe-e4d6-4adb-92c4-c26c220eb297" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_975a0027-d9c3-45ff-a04c-eb0cf1b38216" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromConvertibleDebt_8097333d-4c8d-49bf-90b7-3ab81683a950" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromConvertibleDebt"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_975a0027-d9c3-45ff-a04c-eb0cf1b38216" xlink:to="loc_us-gaap_ProceedsFromConvertibleDebt_8097333d-4c8d-49bf-90b7-3ab81683a950" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_ec48464a-53d3-4abe-9bd7-9717bb58b06c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_975a0027-d9c3-45ff-a04c-eb0cf1b38216" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_ec48464a-53d3-4abe-9bd7-9717bb58b06c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForHedgeFinancingActivities_cf0aecb2-a778-4e3f-ad9c-0e2cf212d488" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsForHedgeFinancingActivities"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_975a0027-d9c3-45ff-a04c-eb0cf1b38216" xlink:to="loc_us-gaap_PaymentsForHedgeFinancingActivities_cf0aecb2-a778-4e3f-ad9c-0e2cf212d488" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_b6d6b22d-d5bc-4f1e-8217-84333c1ee99d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_975a0027-d9c3-45ff-a04c-eb0cf1b38216" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_b6d6b22d-d5bc-4f1e-8217-84333c1ee99d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_850a45b8-a4ac-4570-ab5c-119a6bdd6517" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_975a0027-d9c3-45ff-a04c-eb0cf1b38216" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_850a45b8-a4ac-4570-ab5c-119a6bdd6517" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_33201ee9-d25b-467a-b1d4-8bc5fd61bb73" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_975a0027-d9c3-45ff-a04c-eb0cf1b38216" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_33201ee9-d25b-467a-b1d4-8bc5fd61bb73" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfWarrants_ea51456d-b85e-4007-9a3b-3fe860714acf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProceedsFromIssuanceOfWarrants"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_975a0027-d9c3-45ff-a04c-eb0cf1b38216" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfWarrants_ea51456d-b85e-4007-9a3b-3fe860714acf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeasePrincipalPayments_eabfc0ce-3313-4b4a-bdc3-9c2f754c7078" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeasePrincipalPayments"/>
    <link:calculationArc order="8" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_975a0027-d9c3-45ff-a04c-eb0cf1b38216" xlink:to="loc_us-gaap_FinanceLeasePrincipalPayments_eabfc0ce-3313-4b4a-bdc3-9c2f754c7078" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9be91cca-9bac-4cec-9de5-428fe68f7ccc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5682467d-248a-4e81-bd61-b1a05be022b0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9be91cca-9bac-4cec-9de5-428fe68f7ccc" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_5682467d-248a-4e81-bd61-b1a05be022b0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_da82e9b5-ab7a-4a20-a682-8d12f433d782" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9be91cca-9bac-4cec-9de5-428fe68f7ccc" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_da82e9b5-ab7a-4a20-a682-8d12f433d782" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_88c4001d-c7e0-40ec-a67e-d0efaac22779" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9be91cca-9bac-4cec-9de5-428fe68f7ccc" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_88c4001d-c7e0-40ec-a67e-d0efaac22779" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_d077a40e-38be-4a53-8b64-97be7eca732f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_9be91cca-9bac-4cec-9de5-428fe68f7ccc" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_d077a40e-38be-4a53-8b64-97be7eca732f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_IncreaseDecreaseInAccruedLiabilitiesAndOtherLiabilities_10863df0-229f-48f9-89f3-bde4e6523b1a" xlink:href="dbx-20220630.xsd#dbx_IncreaseDecreaseInAccruedLiabilitiesAndOtherLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_dbx_IncreaseDecreaseInAccruedLiabilitiesAndOtherLiabilities_10863df0-229f-48f9-89f3-bde4e6523b1a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_df5b10d2-834c-481f-bb08-f726d5641621" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_df5b10d2-834c-481f-bb08-f726d5641621" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_f9688757-a633-4dfc-be34-2b348538261e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_f9688757-a633-4dfc-be34-2b348538261e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_ade02c43-bd0a-48d4-8eb6-04ae7f1661da" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_ade02c43-bd0a-48d4-8eb6-04ae7f1661da" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_03530b40-487a-4769-a078-5568a54bbd7a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_03530b40-487a-4769-a078-5568a54bbd7a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_dd29d8a1-4735-4f51-a51e-f21670987a5e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_NetIncomeLoss_dd29d8a1-4735-4f51-a51e-f21670987a5e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalizedContractCostAmortization_41ba9395-4823-4f1a-8255-548ccc7d80b4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CapitalizedContractCostAmortization"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_CapitalizedContractCostAmortization_41ba9395-4823-4f1a-8255-548ccc7d80b4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_1c04fd9a-3e4b-48e5-bdfd-b64f68ef6f97" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_ShareBasedCompensation_1c04fd9a-3e4b-48e5-bdfd-b64f68ef6f97" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_456de7e4-e2a2-4148-8219-f884ae4d69d5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_456de7e4-e2a2-4148-8219-f884ae4d69d5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_IncreaseDecreaseTenantImprovementAllowanceReimbursement_9063e456-2382-4b1c-bcf5-ad0f674d0ec4" xlink:href="dbx-20220630.xsd#dbx_IncreaseDecreaseTenantImprovementAllowanceReimbursement"/>
    <link:calculationArc order="10" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_dbx_IncreaseDecreaseTenantImprovementAllowanceReimbursement_9063e456-2382-4b1c-bcf5-ad0f674d0ec4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables_03e2285b-5936-47a8-b61d-9d3aeeb59366" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables"/>
    <link:calculationArc order="11" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables_03e2285b-5936-47a8-b61d-9d3aeeb59366" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_DeprecationDepletionAndAmortizationExcludingAmortizationOfDeferredSalesCommissions_bbc5e3a4-3472-4f28-869b-47a4fbb115b0" xlink:href="dbx-20220630.xsd#dbx_DeprecationDepletionAndAmortizationExcludingAmortizationOfDeferredSalesCommissions"/>
    <link:calculationArc order="12" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_dbx_DeprecationDepletionAndAmortizationExcludingAmortizationOfDeferredSalesCommissions_bbc5e3a4-3472-4f28-869b-47a4fbb115b0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetImpairmentCharges_309183be-b136-4a84-8190-fb66297cb045" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetImpairmentCharges"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_AssetImpairmentCharges_309183be-b136-4a84-8190-fb66297cb045" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_f0157499-b3e7-45a4-bc78-52f6a1320e2f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability"/>
    <link:calculationArc order="14" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_f0157499-b3e7-45a4-bc78-52f6a1320e2f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_915f905e-b912-4783-8d4f-43e8a6fa473f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:calculationArc order="15" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_915f905e-b912-4783-8d4f-43e8a6fa473f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCosts_de1310bd-82d7-4ba3-89e9-2631853cc6dd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AmortizationOfFinancingCosts"/>
    <link:calculationArc order="16" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_AmortizationOfFinancingCosts_de1310bd-82d7-4ba3-89e9-2631853cc6dd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNiGainLoss_7e2c587e-13c8-4c74-9dae-78e164df89ff" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquitySecuritiesFvNiGainLoss"/>
    <link:calculationArc order="17" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2078b75a-6c2e-4b9e-a8b2-98b754b28880" xlink:to="loc_us-gaap_EquitySecuritiesFvNiGainLoss_7e2c587e-13c8-4c74-9dae-78e164df89ff" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsScheduleofComponentsDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#CashCashEquivalentsandShortTermInvestmentsScheduleofComponentsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsScheduleofComponentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_6c9791e6-0bec-4b1b-b243-4fe888f34cac" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_5da06f8d-7606-46c4-ac6f-67c4712ef2dd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_6c9791e6-0bec-4b1b-b243-4fe888f34cac" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_5da06f8d-7606-46c4-ac6f-67c4712ef2dd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_56e319dc-9be8-4c37-8db7-6f891fcf8514" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_6c9791e6-0bec-4b1b-b243-4fe888f34cac" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_56e319dc-9be8-4c37-8db7-6f891fcf8514" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_13015c16-a034-4821-9b75-907b938cdc88" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_6c9791e6-0bec-4b1b-b243-4fe888f34cac" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_13015c16-a034-4821-9b75-907b938cdc88" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_d4d86585-a0fb-4352-a668-b8ba6baa3cea" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_ebad0189-7413-44d4-8916-b5760aa9ef7b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_d4d86585-a0fb-4352-a668-b8ba6baa3cea" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_ebad0189-7413-44d4-8916-b5760aa9ef7b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost_f09ad0e9-4dbb-4605-aa2c-af051bd8fe5e" xlink:href="dbx-20220630.xsd#dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_2b0a6bee-4f4e-4ddc-b2d7-f521c93d1c4f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost_f09ad0e9-4dbb-4605-aa2c-af051bd8fe5e" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_2b0a6bee-4f4e-4ddc-b2d7-f521c93d1c4f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_107727c9-f3a1-4d65-a189-a108c8e92836" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsAndShortTermInvestments"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost_f09ad0e9-4dbb-4605-aa2c-af051bd8fe5e" xlink:to="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_107727c9-f3a1-4d65-a189-a108c8e92836" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_bdff8488-0efb-407a-a843-60d047e12daa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost_f09ad0e9-4dbb-4605-aa2c-af051bd8fe5e" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_bdff8488-0efb-407a-a843-60d047e12daa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_74155dce-c61a-41a6-a622-1cfe17a5c59d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsAndShortTermInvestments"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_9c579f7c-962c-43c7-b730-3114282ec77c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_74155dce-c61a-41a6-a622-1cfe17a5c59d" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_9c579f7c-962c-43c7-b730-3114282ec77c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_0b643cf8-315a-4c6f-99a5-790fa006f357" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_74155dce-c61a-41a6-a622-1cfe17a5c59d" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_0b643cf8-315a-4c6f-99a5-790fa006f357" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsContractualMaturitiesDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#CashCashEquivalentsandShortTermInvestmentsContractualMaturitiesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsContractualMaturitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_3f79aa48-e4ba-4928-bc94-6b40a4da8553" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsFairValue_0a93d964-bb94-4e06-9b81-a5a0a102e631" xlink:href="dbx-20220630.xsd#dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsFairValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_3f79aa48-e4ba-4928-bc94-6b40a4da8553" xlink:to="loc_dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsFairValue_0a93d964-bb94-4e06-9b81-a5a0a102e631" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_a6a58a47-04a4-4bfe-a7d7-acf9a2c777aa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_3f79aa48-e4ba-4928-bc94-6b40a4da8553" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_a6a58a47-04a4-4bfe-a7d7-acf9a2c777aa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsFairValue_b6601f6c-cb0b-402d-aa3a-ab26b8722a25" xlink:href="dbx-20220630.xsd#dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_3f79aa48-e4ba-4928-bc94-6b40a4da8553" xlink:to="loc_dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsFairValue_b6601f6c-cb0b-402d-aa3a-ab26b8722a25" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_4f55437c-b869-4a9a-b467-30527d5c3ad2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsAmortizedCost_b3dec153-4b7d-46b6-8694-d4dbf55942aa" xlink:href="dbx-20220630.xsd#dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsAmortizedCost"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_4f55437c-b869-4a9a-b467-30527d5c3ad2" xlink:to="loc_dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsAmortizedCost_b3dec153-4b7d-46b6-8694-d4dbf55942aa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost_7da41ae1-bf3f-40e6-a40a-954f7589861d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_4f55437c-b869-4a9a-b467-30527d5c3ad2" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost_7da41ae1-bf3f-40e6-a40a-954f7589861d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsAmortizedCost_3ff360f6-f9a7-4825-b2de-44faf93d57d4" xlink:href="dbx-20220630.xsd#dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsAmortizedCost"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_4f55437c-b869-4a9a-b467-30527d5c3ad2" xlink:to="loc_dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsAmortizedCost_3ff360f6-f9a7-4825-b2de-44faf93d57d4" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsUnrealizedLossPositionAggregatedByInvestmentDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#CashCashEquivalentsandShortTermInvestmentsUnrealizedLossPositionAggregatedByInvestmentDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsUnrealizedLossPositionAggregatedByInvestmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss_f372112d-1044-417e-8c3d-e42ef5cae65d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_75ba8afc-bf14-4279-b372-055a18b56970" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss_f372112d-1044-417e-8c3d-e42ef5cae65d" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_75ba8afc-bf14-4279-b372-055a18b56970" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_dfcd2e88-71dd-4ccf-b6c4-f9af5fe01cac" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPositionAccumulatedLoss_f372112d-1044-417e-8c3d-e42ef5cae65d" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_dfcd2e88-71dd-4ccf-b6c4-f9af5fe01cac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition_e2c43143-bcf4-4a93-a642-fb697affc009" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months_cd9beecd-2e14-4f9c-9c69-9d0df7a892a1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition_e2c43143-bcf4-4a93-a642-fb697affc009" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPositionLessThan12Months_cd9beecd-2e14-4f9c-9c69-9d0df7a892a1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger_be476230-356e-4092-a404-21e3d2b8e8cc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtSecuritiesAvailableForSaleUnrealizedLossPosition_e2c43143-bcf4-4a93-a642-fb697affc009" xlink:to="loc_us-gaap_DebtSecuritiesAvailableForSaleContinuousUnrealizedLossPosition12MonthsOrLonger_be476230-356e-4092-a404-21e3d2b8e8cc" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/FairValueMeasurementsFairValueonRecurringBasisDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#FairValueMeasurementsFairValueonRecurringBasisDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/FairValueMeasurementsFairValueonRecurringBasisDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_955f7091-3196-4174-a784-021f286ec898" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_9664d2d6-290b-42b9-813c-992ff829660d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_955f7091-3196-4174-a784-021f286ec898" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_9664d2d6-290b-42b9-813c-992ff829660d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_20fde107-fa8c-4c4f-906f-fc2ddaaf3efb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_955f7091-3196-4174-a784-021f286ec898" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_20fde107-fa8c-4c4f-906f-fc2ddaaf3efb" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/PropertyandEquipmentNetScheduleofComponentsDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#PropertyandEquipmentNetScheduleofComponentsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/PropertyandEquipmentNetScheduleofComponentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_d51524c5-3efe-4e1d-ba7d-802feba2fa72" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_286a937b-0d77-4a10-b770-b72b4760a719" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_d51524c5-3efe-4e1d-ba7d-802feba2fa72" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_286a937b-0d77-4a10-b770-b72b4760a719" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_09aa635f-e0d6-4c1c-807e-b8e17f30b935" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_d51524c5-3efe-4e1d-ba7d-802feba2fa72" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_09aa635f-e0d6-4c1c-807e-b8e17f30b935" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/BusinessCombinationsScheduleofPurchaseConsiderationDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#BusinessCombinationsScheduleofPurchaseConsiderationDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/BusinessCombinationsScheduleofPurchaseConsiderationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_f1fced88-2b84-4ef2-920b-d2a94d0716c8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationConsiderationTransferred1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPaymentsToAcquireBusinesses_b77af151-6d6e-4453-b3d8-093bea4f2344" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherPaymentsToAcquireBusinesses"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationConsiderationTransferred1_f1fced88-2b84-4ef2-920b-d2a94d0716c8" xlink:to="loc_us-gaap_OtherPaymentsToAcquireBusinesses_b77af151-6d6e-4453-b3d8-093bea4f2344" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_BusinessCombinationConsiderationTransferredStockOptionsAssumed_e2678993-f2dd-44ef-84ba-43ab6a8c0c4d" xlink:href="dbx-20220630.xsd#dbx_BusinessCombinationConsiderationTransferredStockOptionsAssumed"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationConsiderationTransferred1_f1fced88-2b84-4ef2-920b-d2a94d0716c8" xlink:to="loc_dbx_BusinessCombinationConsiderationTransferredStockOptionsAssumed_e2678993-f2dd-44ef-84ba-43ab6a8c0c4d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred_7e876076-9810-438d-9262-b7c6d8a358bf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationConsiderationTransferred1_f1fced88-2b84-4ef2-920b-d2a94d0716c8" xlink:to="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred_7e876076-9810-438d-9262-b7c6d8a358bf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_15851372-3dc8-43dc-9d56-004dd750aca1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquireBusinessesGross"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationConsiderationTransferred1_f1fced88-2b84-4ef2-920b-d2a94d0716c8" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_15851372-3dc8-43dc-9d56-004dd750aca1" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/BusinessCombinationsAssetsAcquiredandLiabilitiesAssumedDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#BusinessCombinationsAssetsAcquiredandLiabilitiesAssumedDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/BusinessCombinationsAssetsAcquiredandLiabilitiesAssumedDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_0f99ba95-37d2-470e-9a08-6a15d27c5414" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_222760cc-a39b-448c-a0c8-d11761a26056" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_0f99ba95-37d2-470e-9a08-6a15d27c5414" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_222760cc-a39b-448c-a0c8-d11761a26056" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_58739274-75da-4b7c-9e7f-9818aefaf334" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_0f99ba95-37d2-470e-9a08-6a15d27c5414" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_58739274-75da-4b7c-9e7f-9818aefaf334" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_16d5d3ab-2f99-40d6-b25f-0d58ff726540" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_d45bd4bb-0d22-43bb-a713-9fd8f65603f7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_16d5d3ab-2f99-40d6-b25f-0d58ff726540" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_d45bd4bb-0d22-43bb-a713-9fd8f65603f7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_29d4313b-7d16-4638-9235-a68472b54a3d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_16d5d3ab-2f99-40d6-b25f-0d58ff726540" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_29d4313b-7d16-4638-9235-a68472b54a3d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_67d0e647-1f25-42ba-b2d9-5909358a1e22" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_16d5d3ab-2f99-40d6-b25f-0d58ff726540" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_67d0e647-1f25-42ba-b2d9-5909358a1e22" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_e4233d67-d0e5-408d-ac21-b93910dfee32" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_329a0d49-b785-4ab1-b15b-2bc98c0c5a28" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_e4233d67-d0e5-408d-ac21-b93910dfee32" xlink:to="loc_us-gaap_Goodwill_329a0d49-b785-4ab1-b15b-2bc98c0c5a28" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_23405cf7-a629-4119-9001-796ac347a1b6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_e4233d67-d0e5-408d-ac21-b93910dfee32" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_23405cf7-a629-4119-9001-796ac347a1b6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_37401c67-cff2-4128-8841-9516dcda77b8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayable_907ac3e6-2750-4b5f-90c1-ddfa88fb73ba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayable"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_37401c67-cff2-4128-8841-9516dcda77b8" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayable_907ac3e6-2750-4b5f-90c1-ddfa88fb73ba" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredRevenue_ae4d744a-7259-49a3-b9e9-6450cc1400ed" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredRevenue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_37401c67-cff2-4128-8841-9516dcda77b8" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredRevenue_ae4d744a-7259-49a3-b9e9-6450cc1400ed" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_ce6c654b-7599-44e4-8a99-498fdcf7b2be" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_37401c67-cff2-4128-8841-9516dcda77b8" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_ce6c654b-7599-44e4-8a99-498fdcf7b2be" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/IntangibleAssetsScheduleofIntangibleAssetsDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#IntangibleAssetsScheduleofIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/IntangibleAssetsScheduleofIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_3ce64859-04b5-4732-9de0-99420f40644a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_adcf6930-13c4-407e-8c11-6ed898164460" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_3ce64859-04b5-4732-9de0-99420f40644a" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_adcf6930-13c4-407e-8c11-6ed898164460" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_4ca221e8-6376-4067-b6df-73a3df724de9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_3ce64859-04b5-4732-9de0-99420f40644a" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_4ca221e8-6376-4067-b6df-73a3df724de9" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/IntangibleAssetsScheduleofFutureAmortizationExpenseDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#IntangibleAssetsScheduleofFutureAmortizationExpenseDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/IntangibleAssetsScheduleofFutureAmortizationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_a35bef0f-8134-48bd-8bfb-f5207f67e680" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_b0189eae-c0a4-4160-9da8-002fe79353e3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_a35bef0f-8134-48bd-8bfb-f5207f67e680" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_b0189eae-c0a4-4160-9da8-002fe79353e3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_0f0f3b03-7643-4ac2-a1e7-b6ae2794a8e1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_a35bef0f-8134-48bd-8bfb-f5207f67e680" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_0f0f3b03-7643-4ac2-a1e7-b6ae2794a8e1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_b606fa92-4aec-497e-9be6-09aded404faa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_a35bef0f-8134-48bd-8bfb-f5207f67e680" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_b606fa92-4aec-497e-9be6-09aded404faa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_f558cbe3-71cd-4a7f-a503-e6f8061068a8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_a35bef0f-8134-48bd-8bfb-f5207f67e680" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_f558cbe3-71cd-4a7f-a503-e6f8061068a8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_a9e22b3a-3124-432f-a5c7-32e6590d158e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_a35bef0f-8134-48bd-8bfb-f5207f67e680" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_a9e22b3a-3124-432f-a5c7-32e6590d158e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_FiniteLivedIntangibleAssetExpectedAmortizationafterYearFour_bac2b702-b3ae-4263-9bd4-092a64898765" xlink:href="dbx-20220630.xsd#dbx_FiniteLivedIntangibleAssetExpectedAmortizationafterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_a35bef0f-8134-48bd-8bfb-f5207f67e680" xlink:to="loc_dbx_FiniteLivedIntangibleAssetExpectedAmortizationafterYearFour_bac2b702-b3ae-4263-9bd4-092a64898765" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/DebtScheduleofConvertibleNotesDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#DebtScheduleofConvertibleNotesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DebtScheduleofConvertibleNotesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_52a5be76-df62-4d0f-b7ae-0ce0df826c25" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnamortizedDebtIssuanceExpense_bd714fdd-0e68-454c-9eb3-04f48f6d974c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_UnamortizedDebtIssuanceExpense"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_52a5be76-df62-4d0f-b7ae-0ce0df826c25" xlink:to="loc_us-gaap_UnamortizedDebtIssuanceExpense_bd714fdd-0e68-454c-9eb3-04f48f6d974c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_3b3d0a05-4dce-4856-bcdc-e9ba5e8fec2f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_52a5be76-df62-4d0f-b7ae-0ce0df826c25" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_3b3d0a05-4dce-4856-bcdc-e9ba5e8fec2f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/DebtLongTermDebtMaturitiesDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#DebtLongTermDebtMaturitiesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DebtLongTermDebtMaturitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_038a57c0-3fae-43da-986c-e5aaf04d5fdd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_2e1b5d5a-1842-4244-9843-a8e26fafcb95" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_038a57c0-3fae-43da-986c-e5aaf04d5fdd" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_2e1b5d5a-1842-4244-9843-a8e26fafcb95" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_2b9b8fde-44f0-422e-8dea-63f1c05d7672" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_038a57c0-3fae-43da-986c-e5aaf04d5fdd" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_2b9b8fde-44f0-422e-8dea-63f1c05d7672" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive_370ce9e5-2d9e-4c9c-b8fe-03c1fb629406" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_038a57c0-3fae-43da-986c-e5aaf04d5fdd" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive_370ce9e5-2d9e-4c9c-b8fe-03c1fb629406" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_393ed352-454c-48e8-ab11-e2ec3b6a7940" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_038a57c0-3fae-43da-986c-e5aaf04d5fdd" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_393ed352-454c-48e8-ab11-e2ec3b6a7940" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_6077a209-2d1a-4776-9b9a-1ede6201fab0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_038a57c0-3fae-43da-986c-e5aaf04d5fdd" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_6077a209-2d1a-4776-9b9a-1ede6201fab0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_3c9dcff4-8af2-4ad2-8105-d5e2378beb2f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_038a57c0-3fae-43da-986c-e5aaf04d5fdd" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_3c9dcff4-8af2-4ad2-8105-d5e2378beb2f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_804c88ab-34d9-49ce-a1bb-a2e47224beec" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_038a57c0-3fae-43da-986c-e5aaf04d5fdd" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_804c88ab-34d9-49ce-a1bb-a2e47224beec" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/LeasesFutureMinimumLeasePaymentsDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#LeasesFutureMinimumLeasePaymentsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/LeasesFutureMinimumLeasePaymentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_e59539f0-ddce-4a92-b0c6-a1ab73ba138b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_9a4b0b3d-4f11-43d2-9f06-4b70098196c9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_e59539f0-ddce-4a92-b0c6-a1ab73ba138b" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_9a4b0b3d-4f11-43d2-9f06-4b70098196c9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_16c2ff88-85e5-4fb0-86af-b3ce4cb7d151" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_e59539f0-ddce-4a92-b0c6-a1ab73ba138b" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_16c2ff88-85e5-4fb0-86af-b3ce4cb7d151" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_4b911568-a88a-48cd-9c7d-90111c3a8fbb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_e59539f0-ddce-4a92-b0c6-a1ab73ba138b" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_4b911568-a88a-48cd-9c7d-90111c3a8fbb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_a385c039-2a7a-4cbd-bad8-13a2cd73e984" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_e59539f0-ddce-4a92-b0c6-a1ab73ba138b" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_a385c039-2a7a-4cbd-bad8-13a2cd73e984" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_fad6f4f1-18a5-467c-8272-8f1d588c9495" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_e59539f0-ddce-4a92-b0c6-a1ab73ba138b" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_fad6f4f1-18a5-467c-8272-8f1d588c9495" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_FinanceLeaseLiabilitytobePaidafterYearFour_1c3faa85-b9a4-42df-861a-f8f3df28d707" xlink:href="dbx-20220630.xsd#dbx_FinanceLeaseLiabilitytobePaidafterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_e59539f0-ddce-4a92-b0c6-a1ab73ba138b" xlink:to="loc_dbx_FinanceLeaseLiabilitytobePaidafterYearFour_1c3faa85-b9a4-42df-861a-f8f3df28d707" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_beb39ed1-0839-4b26-9fd0-fff8da5d8d87" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_c3386bb6-8c43-42d5-a85a-9265ad7b164b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_beb39ed1-0839-4b26-9fd0-fff8da5d8d87" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_c3386bb6-8c43-42d5-a85a-9265ad7b164b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_8f01efb2-5b3a-4fec-aa9e-3cfab0b84aac" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_beb39ed1-0839-4b26-9fd0-fff8da5d8d87" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_8f01efb2-5b3a-4fec-aa9e-3cfab0b84aac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_8fe87ee5-a68d-4c40-a43e-67865bd266fd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_beb39ed1-0839-4b26-9fd0-fff8da5d8d87" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_8fe87ee5-a68d-4c40-a43e-67865bd266fd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_bd8ad2fc-1257-4bb1-a55b-4e53a09cb5e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_beb39ed1-0839-4b26-9fd0-fff8da5d8d87" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_bd8ad2fc-1257-4bb1-a55b-4e53a09cb5e0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_1b5a5eed-cd81-4f06-baef-aabe67d8e1d3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_beb39ed1-0839-4b26-9fd0-fff8da5d8d87" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_1b5a5eed-cd81-4f06-baef-aabe67d8e1d3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_LesseeOperatingLeaseLiabilitytobePaidafterYearFour_0da9f704-b525-4e6e-8253-3647fb76842f" xlink:href="dbx-20220630.xsd#dbx_LesseeOperatingLeaseLiabilitytobePaidafterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_beb39ed1-0839-4b26-9fd0-fff8da5d8d87" xlink:to="loc_dbx_LesseeOperatingLeaseLiabilitytobePaidafterYearFour_0da9f704-b525-4e6e-8253-3647fb76842f" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/LeasesFutureSubtenantPaymentsReceivableDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#LeasesFutureSubtenantPaymentsReceivableDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/LeasesFutureSubtenantPaymentsReceivableDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_bcc2be1b-409f-435e-a5b6-1fb59381d46f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceived"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_OperatingLeaseLessorOperatingLeasePaymentsToBeReceivedLessLeaseIncentives_5271f523-8009-45ae-af49-d18b0de141ac" xlink:href="dbx-20220630.xsd#dbx_OperatingLeaseLessorOperatingLeasePaymentsToBeReceivedLessLeaseIncentives"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_bcc2be1b-409f-435e-a5b6-1fb59381d46f" xlink:to="loc_dbx_OperatingLeaseLessorOperatingLeasePaymentsToBeReceivedLessLeaseIncentives_5271f523-8009-45ae-af49-d18b0de141ac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_LessorOperatingLeaseLeaseReceivableUndiscountedExcessAmount_de8aa91d-e885-4d9b-abc7-d124e6894524" xlink:href="dbx-20220630.xsd#dbx_LessorOperatingLeaseLeaseReceivableUndiscountedExcessAmount"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_bcc2be1b-409f-435e-a5b6-1fb59381d46f" xlink:to="loc_dbx_LessorOperatingLeaseLeaseReceivableUndiscountedExcessAmount_de8aa91d-e885-4d9b-abc7-d124e6894524" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/LeasesFutureSubtenantPaymentsReceivableDetails_1" xlink:type="simple" xlink:href="dbx-20220630.xsd#LeasesFutureSubtenantPaymentsReceivableDetails_1"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/LeasesFutureSubtenantPaymentsReceivableDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_cf371e00-a23e-4fa8-b14d-8677e858cdd9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceived"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear_54e8ed05-345b-40f8-a2c2-a7fe199e8334" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_cf371e00-a23e-4fa8-b14d-8677e858cdd9" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear_54e8ed05-345b-40f8-a2c2-a7fe199e8334" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedFourYears_2098ebb6-a1b1-48f8-9a45-b7c06ef61ea8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedFourYears"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_cf371e00-a23e-4fa8-b14d-8677e858cdd9" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedFourYears_2098ebb6-a1b1-48f8-9a45-b7c06ef61ea8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths_2bac458f-9cc1-4899-a9a0-fdb4187117a7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_cf371e00-a23e-4fa8-b14d-8677e858cdd9" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths_2bac458f-9cc1-4899-a9a0-fdb4187117a7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedTwoYears_727b746a-4c4e-455f-9f72-c62a74f3869b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedTwoYears"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_cf371e00-a23e-4fa8-b14d-8677e858cdd9" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedTwoYears_727b746a-4c4e-455f-9f72-c62a74f3869b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_LessorOperatingLeasePaymentsToBeReceivedAfterYearFour_14b8daf9-c32b-4a3f-ae34-1e8f4d399a8c" xlink:href="dbx-20220630.xsd#dbx_LessorOperatingLeasePaymentsToBeReceivedAfterYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_cf371e00-a23e-4fa8-b14d-8677e858cdd9" xlink:to="loc_dbx_LessorOperatingLeasePaymentsToBeReceivedAfterYearFour_14b8daf9-c32b-4a3f-ae34-1e8f4d399a8c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedThreeYears_7af97857-e8f1-496e-be71-9d06f93db9a2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedThreeYears"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_cf371e00-a23e-4fa8-b14d-8677e858cdd9" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedThreeYears_7af97857-e8f1-496e-be71-9d06f93db9a2" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/AccruedandOtherCurrentLiabilitiesDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#AccruedandOtherCurrentLiabilitiesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/AccruedandOtherCurrentLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_2564e36a-d533-41fa-aad8-6e63b196464a" xlink:href="dbx-20220630.xsd#dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedProfessionalFeesCurrent_f522824f-5965-4c24-aca8-e9ea81c33957" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedProfessionalFeesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_2564e36a-d533-41fa-aad8-6e63b196464a" xlink:to="loc_us-gaap_AccruedProfessionalFeesCurrent_f522824f-5965-4c24-aca8-e9ea81c33957" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_OtherAccruedLiabilitiesAndOtherLiabilitiesCurrent_0f4d56c2-1182-4f28-9286-8e23d7115edc" xlink:href="dbx-20220630.xsd#dbx_OtherAccruedLiabilitiesAndOtherLiabilitiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_2564e36a-d533-41fa-aad8-6e63b196464a" xlink:to="loc_dbx_OtherAccruedLiabilitiesAndOtherLiabilitiesCurrent_0f4d56c2-1182-4f28-9286-8e23d7115edc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccrualForTaxesOtherThanIncomeTaxesCurrent_67884f6a-a772-4398-87fc-c9e61c8f7613" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccrualForTaxesOtherThanIncomeTaxesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_2564e36a-d533-41fa-aad8-6e63b196464a" xlink:to="loc_us-gaap_AccrualForTaxesOtherThanIncomeTaxesCurrent_67884f6a-a772-4398-87fc-c9e61c8f7613" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/NetIncomePerShareScheduleofEarningsPerShareBasicandDilutedDetails" xlink:type="simple" xlink:href="dbx-20220630.xsd#NetIncomePerShareScheduleofEarningsPerShareBasicandDilutedDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/NetIncomePerShareScheduleofEarningsPerShareBasicandDilutedDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_5d63f342-19f8-4965-a9b4-d4d39a108233" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_216e5b1f-31d8-4668-8e31-d17a159cbf4f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_5d63f342-19f8-4965-a9b4-d4d39a108233" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_216e5b1f-31d8-4668-8e31-d17a159cbf4f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_c626feb5-bead-4fdd-809c-bf197ba83705" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_5d63f342-19f8-4965-a9b4-d4d39a108233" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_c626feb5-bead-4fdd-809c-bf197ba83705" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_IncrementalCommonSharesAttributabletoDilutiveEffectofConversionofCommonStock_3044dab3-0e11-4dc3-95ae-1a43c0ff0a43" xlink:href="dbx-20220630.xsd#dbx_IncrementalCommonSharesAttributabletoDilutiveEffectofConversionofCommonStock"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_5d63f342-19f8-4965-a9b4-d4d39a108233" xlink:to="loc_dbx_IncrementalCommonSharesAttributabletoDilutiveEffectofConversionofCommonStock_3044dab3-0e11-4dc3-95ae-1a43c0ff0a43" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_ba1d3654-cbae-4729-aba4-65ad30de7520" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_1e81b422-8599-45c5-9589-7f04ff9293c4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_ba1d3654-cbae-4729-aba4-65ad30de7520" xlink:to="loc_us-gaap_NetIncomeLoss_1e81b422-8599-45c5-9589-7f04ff9293c4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DilutiveSecuritiesEffectOnBasicEarningsPerShareOther_cba31cda-9346-4bce-945e-931dd73a4008" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DilutiveSecuritiesEffectOnBasicEarningsPerShareOther"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_ba1d3654-cbae-4729-aba4-65ad30de7520" xlink:to="loc_us-gaap_DilutiveSecuritiesEffectOnBasicEarningsPerShareOther_cba31cda-9346-4bce-945e-931dd73a4008" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_DilutiveSecuritiesEffectOnBasicEPSDilutiveEffectOfReallocation_94f83619-b9c1-4840-a493-02c6da57cc95" xlink:href="dbx-20220630.xsd#dbx_DilutiveSecuritiesEffectOnBasicEPSDilutiveEffectOfReallocation"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_ba1d3654-cbae-4729-aba4-65ad30de7520" xlink:to="loc_dbx_DilutiveSecuritiesEffectOnBasicEPSDilutiveEffectOfReallocation_94f83619-b9c1-4840-a493-02c6da57cc95" xlink:type="arc"/>
  </link:calculationLink>
</link:linkbase>
