<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2021 Workiva-->
<!--r:a6bfdae8-3dcb-40c6-95f0-10e30f2bb8c5,g:2831d6a8-3d33-4574-a635-8b6e4879e6b7-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.dropbox.com/role/CoverPage" xlink:type="simple" xlink:href="dbx-20210331.xsd#CoverPage"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CoverPage" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedBalanceSheets" xlink:type="simple" xlink:href="dbx-20210331.xsd#CondensedConsolidatedBalanceSheets"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_62202ade-924e-46c2-a0d0-18e2bc02c8af" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_d3849b16-847b-442a-87b3-e08c85772492" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_62202ade-924e-46c2-a0d0-18e2bc02c8af" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_d3849b16-847b-442a-87b3-e08c85772492" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_88e3dd7e-1341-493d-b06f-ba6610d99f1f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_62202ade-924e-46c2-a0d0-18e2bc02c8af" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecuritiesCurrent_88e3dd7e-1341-493d-b06f-ba6610d99f1f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_147b26ec-c788-4704-b158-c1d23ab17bc8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_62202ade-924e-46c2-a0d0-18e2bc02c8af" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_147b26ec-c788-4704-b158-c1d23ab17bc8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_80d20b3c-0ab6-4097-815f-171e3b9ec75b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsCurrent_62202ade-924e-46c2-a0d0-18e2bc02c8af" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_80d20b3c-0ab6-4097-815f-171e3b9ec75b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_e0690c62-2c0f-416b-b9bb-cf6d78cc294f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Assets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_54f2d1f8-5a04-4ebf-b299-c2bae8c5c2d7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e0690c62-2c0f-416b-b9bb-cf6d78cc294f" xlink:to="loc_us-gaap_AssetsCurrent_54f2d1f8-5a04-4ebf-b299-c2bae8c5c2d7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_e3cb62d2-14dc-421c-bd9c-eb829cb8330f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e0690c62-2c0f-416b-b9bb-cf6d78cc294f" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_e3cb62d2-14dc-421c-bd9c-eb829cb8330f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_b001b89f-a10f-492c-84dd-c2c9212fd06e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e0690c62-2c0f-416b-b9bb-cf6d78cc294f" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_b001b89f-a10f-492c-84dd-c2c9212fd06e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_8a990e18-7c11-4e7b-a6a9-a24cd8b7f441" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e0690c62-2c0f-416b-b9bb-cf6d78cc294f" xlink:to="loc_us-gaap_Goodwill_8a990e18-7c11-4e7b-a6a9-a24cd8b7f441" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_c93e6664-2005-49b2-b278-69f0418aa942" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e0690c62-2c0f-416b-b9bb-cf6d78cc294f" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_c93e6664-2005-49b2-b278-69f0418aa942" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_d5234adf-26b0-4f8a-a6fd-9fbaba8822ed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_e0690c62-2c0f-416b-b9bb-cf6d78cc294f" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_d5234adf-26b0-4f8a-a6fd-9fbaba8822ed" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_694e47a1-223b-4d2e-b8dd-96baba8f514d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_6f7fcb11-44b1-4a33-8ff3-89137bcd3716" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_694e47a1-223b-4d2e-b8dd-96baba8f514d" xlink:to="loc_us-gaap_StockholdersEquity_6f7fcb11-44b1-4a33-8ff3-89137bcd3716" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_5e801683-1b02-42b2-b303-c36d1e4c8218" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Liabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_694e47a1-223b-4d2e-b8dd-96baba8f514d" xlink:to="loc_us-gaap_Liabilities_5e801683-1b02-42b2-b303-c36d1e4c8218" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_9a438949-d604-408d-b646-86937fe31b35" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_694e47a1-223b-4d2e-b8dd-96baba8f514d" xlink:to="loc_us-gaap_CommitmentsAndContingencies_9a438949-d604-408d-b646-86937fe31b35" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_31219619-69fd-43f9-9112-a20d7d78aa6a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_StockholdersEquity"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_68443536-36e7-40c4-81af-50a7a2e80440" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_31219619-69fd-43f9-9112-a20d7d78aa6a" xlink:to="loc_us-gaap_AdditionalPaidInCapital_68443536-36e7-40c4-81af-50a7a2e80440" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_b0782d97-f124-4e51-8423-e045e95a58ec" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_31219619-69fd-43f9-9112-a20d7d78aa6a" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_b0782d97-f124-4e51-8423-e045e95a58ec" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_ef515a71-1aa8-45d1-84bb-ce2c66549d88" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_31219619-69fd-43f9-9112-a20d7d78aa6a" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_ef515a71-1aa8-45d1-84bb-ce2c66549d88" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_9ea936d0-48f8-48b9-95c3-e30ad15c46ee" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_92ac975a-d0fb-4ccd-9433-51d01be8d8c4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_9ea936d0-48f8-48b9-95c3-e30ad15c46ee" xlink:to="loc_us-gaap_AccountsPayableCurrent_92ac975a-d0fb-4ccd-9433-51d01be8d8c4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_f87955b8-8723-4635-8022-aa3d67d29544" xlink:href="dbx-20210331.xsd#dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_9ea936d0-48f8-48b9-95c3-e30ad15c46ee" xlink:to="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_f87955b8-8723-4635-8022-aa3d67d29544" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_1c64382b-9cbd-47c8-a676-6b39fac6bf8a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_9ea936d0-48f8-48b9-95c3-e30ad15c46ee" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_1c64382b-9cbd-47c8-a676-6b39fac6bf8a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_5f0ce252-d21b-45fa-a55a-322b4642eb88" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_9ea936d0-48f8-48b9-95c3-e30ad15c46ee" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_5f0ce252-d21b-45fa-a55a-322b4642eb88" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityCurrent_cb5d16a8-86a8-4311-9494-80b0ed53558f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityCurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_9ea936d0-48f8-48b9-95c3-e30ad15c46ee" xlink:to="loc_us-gaap_FinanceLeaseLiabilityCurrent_cb5d16a8-86a8-4311-9494-80b0ed53558f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_64007523-e81b-48e1-8ba0-a41483f97c3a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesCurrent_9ea936d0-48f8-48b9-95c3-e30ad15c46ee" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_64007523-e81b-48e1-8ba0-a41483f97c3a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_5ce17a74-1f07-493b-a0b0-7472001a40b4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Liabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_f9d19faf-2984-489d-8a2f-46fae9f91152" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_5ce17a74-1f07-493b-a0b0-7472001a40b4" xlink:to="loc_us-gaap_LiabilitiesCurrent_f9d19faf-2984-489d-8a2f-46fae9f91152" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_b5779634-2d6a-4556-9cf2-eaa464ccf0bf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_5ce17a74-1f07-493b-a0b0-7472001a40b4" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_b5779634-2d6a-4556-9cf2-eaa464ccf0bf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_16c19383-a5da-4daf-a8ef-91528bf2dd6b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityNoncurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_5ce17a74-1f07-493b-a0b0-7472001a40b4" xlink:to="loc_us-gaap_FinanceLeaseLiabilityNoncurrent_16c19383-a5da-4daf-a8ef-91528bf2dd6b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_fd5028c7-e7ed-403a-9d93-1f07f8285988" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_5ce17a74-1f07-493b-a0b0-7472001a40b4" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_fd5028c7-e7ed-403a-9d93-1f07f8285988" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConvertibleDebtNoncurrent_009a2f2f-f56e-45e9-9751-d7daa174bcd1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ConvertibleDebtNoncurrent"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_5ce17a74-1f07-493b-a0b0-7472001a40b4" xlink:to="loc_us-gaap_ConvertibleDebtNoncurrent_009a2f2f-f56e-45e9-9751-d7daa174bcd1" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedStatementsofOperations" xlink:type="simple" xlink:href="dbx-20210331.xsd#CondensedConsolidatedStatementsofOperations"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedStatementsofOperations" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_1fdf1168-f530-4f9a-a708-b4bca491d6c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GrossProfit"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_387c6383-6834-4150-be00-492a0376bf88" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_1fdf1168-f530-4f9a-a708-b4bca491d6c9" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_387c6383-6834-4150-be00-492a0376bf88" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_98607254-02ff-4167-9648-1eae24b2ec54" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_GrossProfit_1fdf1168-f530-4f9a-a708-b4bca491d6c9" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_98607254-02ff-4167-9648-1eae24b2ec54" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_c6db3881-5386-4258-9e48-753873244441" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_5e75ec8d-3d69-407e-afde-1e6899a750e0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_c6db3881-5386-4258-9e48-753873244441" xlink:to="loc_us-gaap_OperatingIncomeLoss_5e75ec8d-3d69-407e-afde-1e6899a750e0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_f5c00826-3235-4a78-b404-c2fca9a1558f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_InterestIncomeExpenseNonoperatingNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_c6db3881-5386-4258-9e48-753873244441" xlink:to="loc_us-gaap_InterestIncomeExpenseNonoperatingNet_f5c00826-3235-4a78-b404-c2fca9a1558f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNonoperatingIncomeExpense_c3c5d5ae-c78a-49e0-8e0f-a16fc93127d7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNonoperatingIncomeExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_c6db3881-5386-4258-9e48-753873244441" xlink:to="loc_us-gaap_OtherNonoperatingIncomeExpense_c3c5d5ae-c78a-49e0-8e0f-a16fc93127d7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_1b25dd1f-f1f7-403b-b40c-98ebaeb4db7d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_46d8f94b-85ba-4dc8-afd0-989252784a02" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingExpenses"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_1b25dd1f-f1f7-403b-b40c-98ebaeb4db7d" xlink:to="loc_us-gaap_OperatingExpenses_46d8f94b-85ba-4dc8-afd0-989252784a02" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_9b927670-4aa7-492b-8a63-ec2c46eee852" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GrossProfit"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingIncomeLoss_1b25dd1f-f1f7-403b-b40c-98ebaeb4db7d" xlink:to="loc_us-gaap_GrossProfit_9b927670-4aa7-492b-8a63-ec2c46eee852" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_579f5983-c7f2-44e8-987e-13f8b3dea1c1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_084c143c-736b-46a6-a0d2-371e7299f4c6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_579f5983-c7f2-44e8-987e-13f8b3dea1c1" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_084c143c-736b-46a6-a0d2-371e7299f4c6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_4dbdf57d-ce34-45b2-90ef-393b60492b53" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_579f5983-c7f2-44e8-987e-13f8b3dea1c1" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_4dbdf57d-ce34-45b2-90ef-393b60492b53" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_f48bd7b9-060c-4667-9668-25106222b9ff" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OperatingExpenses"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingAndMarketingExpense_0b9166b6-cc06-4265-bb23-b3ec52a54fac" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_SellingAndMarketingExpense"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_f48bd7b9-060c-4667-9668-25106222b9ff" xlink:to="loc_us-gaap_SellingAndMarketingExpense_0b9166b6-cc06-4265-bb23-b3ec52a54fac" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_8b2249fc-5fc0-4d66-9c55-9b3bc3b69c4f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_f48bd7b9-060c-4667-9668-25106222b9ff" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_8b2249fc-5fc0-4d66-9c55-9b3bc3b69c4f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_a53ee43d-79c0-4c05-b881-84a31b75ceed" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_f48bd7b9-060c-4667-9668-25106222b9ff" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_a53ee43d-79c0-4c05-b881-84a31b75ceed" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairmentOfRealEstate_96803a64-8b56-48af-a3f1-a7943937268b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ImpairmentOfRealEstate"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OperatingExpenses_f48bd7b9-060c-4667-9668-25106222b9ff" xlink:to="loc_us-gaap_ImpairmentOfRealEstate_96803a64-8b56-48af-a3f1-a7943937268b" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedStatementsofOperationsParenthetical" xlink:type="simple" xlink:href="dbx-20210331.xsd#CondensedConsolidatedStatementsofOperationsParenthetical"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedStatementsofOperationsParenthetical" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedStatementsofComprehensiveIncome" xlink:type="simple" xlink:href="dbx-20210331.xsd#CondensedConsolidatedStatementsofComprehensiveIncome"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedStatementsofComprehensiveIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_f481ddc1-2b53-40a2-8a2d-a63d12d653d2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_014f6055-5cfd-43cb-a7b0-dba2dee470ea" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_f481ddc1-2b53-40a2-8a2d-a63d12d653d2" xlink:to="loc_us-gaap_NetIncomeLoss_014f6055-5cfd-43cb-a7b0-dba2dee470ea" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_76fad776-c684-4996-9b7c-54e5ae7c9d30" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_f481ddc1-2b53-40a2-8a2d-a63d12d653d2" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_76fad776-c684-4996-9b7c-54e5ae7c9d30" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_dfd0bfdd-4f8c-42e5-8477-38e4ebd9a86d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_5b381ca9-3e89-4ed9-bc29-e5d0cb140915" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_dfd0bfdd-4f8c-42e5-8477-38e4ebd9a86d" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_5b381ca9-3e89-4ed9-bc29-e5d0cb140915" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_c224e17f-a761-44f0-923d-76c7c64a6369" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_dfd0bfdd-4f8c-42e5-8477-38e4ebd9a86d" xlink:to="loc_us-gaap_OtherComprehensiveIncomeAvailableforsaleSecuritiesAdjustmentNetOfTaxPortionAttributableToParent_c224e17f-a761-44f0-923d-76c7c64a6369" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedStatementsofStockholdersDeficitEquity" xlink:type="simple" xlink:href="dbx-20210331.xsd#CondensedConsolidatedStatementsofStockholdersDeficitEquity"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedStatementsofStockholdersDeficitEquity" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="dbx-20210331.xsd#CondensedConsolidatedStatementsofCashFlows"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CondensedConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9b08c73f-ea2e-45ba-8025-35155ba67dc0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_2ac8d39f-f3b9-4d2b-bb80-1b6bab0453e2" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9b08c73f-ea2e-45ba-8025-35155ba67dc0" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesNetOfCashAcquired_2ac8d39f-f3b9-4d2b-bb80-1b6bab0453e2" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_7c8fa2a0-4616-4231-bacb-d2c62bc1547e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9b08c73f-ea2e-45ba-8025-35155ba67dc0" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecuritiesDebt_7c8fa2a0-4616-4231-bacb-d2c62bc1547e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_b3079129-7735-4bbc-a06b-f878917ed0a6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForProceedsFromOtherInvestingActivities"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9b08c73f-ea2e-45ba-8025-35155ba67dc0" xlink:to="loc_us-gaap_PaymentsForProceedsFromOtherInvestingActivities_b3079129-7735-4bbc-a06b-f878917ed0a6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_96e6e58d-57be-429a-8631-ea0d1a522616" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9b08c73f-ea2e-45ba-8025-35155ba67dc0" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_96e6e58d-57be-429a-8631-ea0d1a522616" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments_a3390938-fec2-43ae-8689-a041eb2dc94b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9b08c73f-ea2e-45ba-8025-35155ba67dc0" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfShorttermInvestments_a3390938-fec2-43ae-8689-a041eb2dc94b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromSaleOfShortTermInvestments_66f5d96d-2c26-4289-9425-570fcd4b66fa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromSaleOfShortTermInvestments"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_9b08c73f-ea2e-45ba-8025-35155ba67dc0" xlink:to="loc_us-gaap_ProceedsFromSaleOfShortTermInvestments_66f5d96d-2c26-4289-9425-570fcd4b66fa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_1a3e0267-9cbc-4f58-8ef5-d5f6ce318d75" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_3697838c-1f26-49fc-8533-2b2ff815f170" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_1a3e0267-9cbc-4f58-8ef5-d5f6ce318d75" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_3697838c-1f26-49fc-8533-2b2ff815f170" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_069b8ae4-925f-4ca6-b631-acd7ce76e956" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_1a3e0267-9cbc-4f58-8ef5-d5f6ce318d75" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_069b8ae4-925f-4ca6-b631-acd7ce76e956" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_5a5ecff2-3b7d-4fba-a591-e8945823c894" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_1a3e0267-9cbc-4f58-8ef5-d5f6ce318d75" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_5a5ecff2-3b7d-4fba-a591-e8945823c894" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_5aecc2c1-1ddf-4eda-88bd-3431b9ba8065" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_1a3e0267-9cbc-4f58-8ef5-d5f6ce318d75" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_5aecc2c1-1ddf-4eda-88bd-3431b9ba8065" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_IncreaseDecreaseInAccruedLiabilitiesAndOtherLiabilities_e6b9524e-b114-498a-a0eb-7785cbabfbc3" xlink:href="dbx-20210331.xsd#dbx_IncreaseDecreaseInAccruedLiabilitiesAndOtherLiabilities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_dbx_IncreaseDecreaseInAccruedLiabilitiesAndOtherLiabilities_e6b9524e-b114-498a-a0eb-7785cbabfbc3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_6715fff4-0392-4ce0-88e4-a7b8e073a7d1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_IncreaseDecreaseInEmployeeRelatedLiabilities_6715fff4-0392-4ce0-88e4-a7b8e073a7d1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherNoncashIncomeExpense_e7d10e1d-c62d-4039-82b3-a8ae8474345f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherNoncashIncomeExpense"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_OtherNoncashIncomeExpense_e7d10e1d-c62d-4039-82b3-a8ae8474345f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_fc5bab09-5dd8-4d4f-a8e0-eb14da4690ca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_fc5bab09-5dd8-4d4f-a8e0-eb14da4690ca" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_fc18ec82-c82c-4558-8fa8-ad4debd1498b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherNoncurrentLiabilities_fc18ec82-c82c-4558-8fa8-ad4debd1498b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_f2451b29-0203-408e-a257-108b053267fa" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_NetIncomeLoss_f2451b29-0203-408e-a257-108b053267fa" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CapitalizedContractCostAmortization_58b0854a-97e9-442a-bc84-c1d258d1ed9b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CapitalizedContractCostAmortization"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_CapitalizedContractCostAmortization_58b0854a-97e9-442a-bc84-c1d258d1ed9b" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_0980c56f-bafd-410d-9d0b-1cdd2c2c3ece" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ShareBasedCompensation"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_ShareBasedCompensation_0980c56f-bafd-410d-9d0b-1cdd2c2c3ece" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayable_7621d264-9438-4e01-970f-b85cb73fd5b0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsPayable"/>
    <link:calculationArc order="9" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayable_7621d264-9438-4e01-970f-b85cb73fd5b0" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquitySecuritiesFvNiGainLoss_c65700e5-0c3f-4292-9175-430a5cb50d8f" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_EquitySecuritiesFvNiGainLoss"/>
    <link:calculationArc order="10" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_EquitySecuritiesFvNiGainLoss_c65700e5-0c3f-4292-9175-430a5cb50d8f" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_IncreaseDecreaseTenantImprovementAllowanceReimbursement_5e317cf9-1570-4610-8649-f45aa1ca0d78" xlink:href="dbx-20210331.xsd#dbx_IncreaseDecreaseTenantImprovementAllowanceReimbursement"/>
    <link:calculationArc order="11" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_dbx_IncreaseDecreaseTenantImprovementAllowanceReimbursement_5e317cf9-1570-4610-8649-f45aa1ca0d78" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables_c9324de2-ee0a-49cc-a79f-355000cd6dca" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables"/>
    <link:calculationArc order="12" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsAndOtherReceivables_c9324de2-ee0a-49cc-a79f-355000cd6dca" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_DeprecationDepletionAndAmortizationExcludingAmortizationOfDeferredSalesCommissions_bdbbe17e-61d7-4481-b0c1-21a472748010" xlink:href="dbx-20210331.xsd#dbx_DeprecationDepletionAndAmortizationExcludingAmortizationOfDeferredSalesCommissions"/>
    <link:calculationArc order="13" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_dbx_DeprecationDepletionAndAmortizationExcludingAmortizationOfDeferredSalesCommissions_bdbbe17e-61d7-4481-b0c1-21a472748010" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairmentOfRealEstate_c64d1a88-e116-49fb-b010-50dd481f9ce3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ImpairmentOfRealEstate"/>
    <link:calculationArc order="14" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_ImpairmentOfRealEstate_c64d1a88-e116-49fb-b010-50dd481f9ce3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_06f8f2bc-ae49-4af7-b9cc-68a994dd5fff" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInContractWithCustomerLiability"/>
    <link:calculationArc order="15" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_IncreaseDecreaseInContractWithCustomerLiability_06f8f2bc-ae49-4af7-b9cc-68a994dd5fff" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_1009f3df-4bda-468e-91c1-ca74183e452d" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets"/>
    <link:calculationArc order="16" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_1009f3df-4bda-468e-91c1-ca74183e452d" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AmortizationOfFinancingCosts_f50d621e-4cae-42b4-b919-beecc4dcd9fe" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AmortizationOfFinancingCosts"/>
    <link:calculationArc order="17" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_2867f3ff-342d-406f-b24a-c10d97c1d4ad" xlink:to="loc_us-gaap_AmortizationOfFinancingCosts_f50d621e-4cae-42b4-b919-beecc4dcd9fe" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromConvertibleDebt_0d43d9dd-ef16-419e-9194-97f9185b785e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromConvertibleDebt"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:to="loc_us-gaap_ProceedsFromConvertibleDebt_0d43d9dd-ef16-419e-9194-97f9185b785e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_2b9e0ce5-f5b8-4b22-b86c-63bae6225f3a" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:to="loc_us-gaap_PaymentsRelatedToTaxWithholdingForShareBasedCompensation_2b9e0ce5-f5b8-4b22-b86c-63bae6225f3a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForHedgeFinancingActivities_0e16a0ed-df5e-4bf5-81e1-3397d5bf7b04" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForHedgeFinancingActivities"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:to="loc_us-gaap_PaymentsForHedgeFinancingActivities_0e16a0ed-df5e-4bf5-81e1-3397d5bf7b04" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsOfDebtIssuanceCosts_5fa435b4-f1b6-4fe5-8c30-71e700cfa288" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsOfDebtIssuanceCosts"/>
    <link:calculationArc order="4" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:to="loc_us-gaap_PaymentsOfDebtIssuanceCosts_5fa435b4-f1b6-4fe5-8c30-71e700cfa288" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_5b4d22a9-6615-4cba-b147-9eecf12eec20" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsForRepurchaseOfCommonStock"/>
    <link:calculationArc order="5" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:to="loc_us-gaap_PaymentsForRepurchaseOfCommonStock_5b4d22a9-6615-4cba-b147-9eecf12eec20" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_8c9b4a05-4a3e-4dfa-99c9-55590749df87" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromPaymentsForOtherFinancingActivities"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:to="loc_us-gaap_ProceedsFromPaymentsForOtherFinancingActivities_8c9b4a05-4a3e-4dfa-99c9-55590749df87" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_27403b39-fc4d-47e8-9181-1b3eb4433da5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfCommonStock"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfCommonStock_27403b39-fc4d-47e8-9181-1b3eb4433da5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfWarrants_439f6221-222a-43e3-9d18-eb2349cd00dc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_ProceedsFromIssuanceOfWarrants"/>
    <link:calculationArc order="8" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfWarrants_439f6221-222a-43e3-9d18-eb2349cd00dc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeasePrincipalPayments_29db978d-86a6-4b1f-b5ba-7a5bbcf2c848" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeasePrincipalPayments"/>
    <link:calculationArc order="9" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_3c13b24a-dca2-46f7-9941-901ea67239c4" xlink:to="loc_us-gaap_FinanceLeasePrincipalPayments_29db978d-86a6-4b1f-b5ba-7a5bbcf2c848" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPolicies"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPolicies" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesPolicies" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesPolicies"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesPolicies" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesForeignCurrencyTransactionsDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesForeignCurrencyTransactionsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesForeignCurrencyTransactionsDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesRevenueRecognitionDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesRevenueRecognitionDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesRevenueRecognitionDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesRevenueRecognitionDetails_1" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesRevenueRecognitionDetails_1"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesRevenueRecognitionDetails_1" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesStockbasedCompensationDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesStockbasedCompensationDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesStockbasedCompensationDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesConcentrationofCreditRiskDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesConcentrationofCreditRiskDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesConcentrationofCreditRiskDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesDeferredCommissionsNetDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesDeferredCommissionsNetDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesDeferredCommissionsNetDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesPropertyandEquipmentNetDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesPropertyandEquipmentNetDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesPropertyandEquipmentNetDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesLeaseObligationsDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesLeaseObligationsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DescriptionoftheBusinessandSummaryofSignificantAccountingPoliciesLeaseObligationsDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestments" xlink:type="simple" xlink:href="dbx-20210331.xsd#CashCashEquivalentsandShortTermInvestments"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestments" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#CashCashEquivalentsandShortTermInvestmentsTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsScheduleofComponentsDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#CashCashEquivalentsandShortTermInvestmentsScheduleofComponentsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsScheduleofComponentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_82ea9c63-cb26-4823-a6ed-626a26cbd432" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_6c5adb22-c2e4-4ae4-8560-fade3d18c9b6" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_82ea9c63-cb26-4823-a6ed-626a26cbd432" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_6c5adb22-c2e4-4ae4-8560-fade3d18c9b6" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_be6cf7ce-49e0-4251-b3df-b99cacaa0e7c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_82ea9c63-cb26-4823-a6ed-626a26cbd432" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_be6cf7ce-49e0-4251-b3df-b99cacaa0e7c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_cd3938af-2fde-4b82-80b1-08ee538203a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_82ea9c63-cb26-4823-a6ed-626a26cbd432" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_cd3938af-2fde-4b82-80b1-08ee538203a9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_45e08380-4ad2-48b4-a9ce-f59ee8d70d57" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsAndShortTermInvestments"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_538dfa3e-7f8f-45c4-a121-d6d45fc7c712" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_45e08380-4ad2-48b4-a9ce-f59ee8d70d57" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_538dfa3e-7f8f-45c4-a121-d6d45fc7c712" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_e6d9c619-f63f-47fb-a568-d45d556ac375" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_45e08380-4ad2-48b4-a9ce-f59ee8d70d57" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_e6d9c619-f63f-47fb-a568-d45d556ac375" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost_85759558-ba7a-4f6c-8de7-cbb1a3a03c9b" xlink:href="dbx-20210331.xsd#dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_5f8e4af7-a82b-4167-8ce2-129546ff2fcb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost_85759558-ba7a-4f6c-8de7-cbb1a3a03c9b" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedGainBeforeTax_5f8e4af7-a82b-4167-8ce2-129546ff2fcb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_f4afcc0e-196b-42a1-b37a-18615d3fd2da" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashCashEquivalentsAndShortTermInvestments"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost_85759558-ba7a-4f6c-8de7-cbb1a3a03c9b" xlink:to="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_f4afcc0e-196b-42a1-b37a-18615d3fd2da" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_405add1a-d15f-4bd8-b8dd-1f5022052ccb" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_CashCashEquivalentsAndShortTermInvestmentsAmortizedCost_85759558-ba7a-4f6c-8de7-cbb1a3a03c9b" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAccumulatedGrossUnrealizedLossBeforeTax_405add1a-d15f-4bd8-b8dd-1f5022052ccb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_e7ee86bd-5820-4c86-8c3f-ea9d254df843" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_0dee2673-5a8c-4b41-a9e0-2eaa629bc62c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_e7ee86bd-5820-4c86-8c3f-ea9d254df843" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_0dee2673-5a8c-4b41-a9e0-2eaa629bc62c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsNarrativeDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#CashCashEquivalentsandShortTermInvestmentsNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsContractualMaturitiesDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#CashCashEquivalentsandShortTermInvestmentsContractualMaturitiesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CashCashEquivalentsandShortTermInvestmentsContractualMaturitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_4632b8ae-7a45-4939-a631-01f5f7493820" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsFairValue_e906bb91-7f7e-4d58-b12f-1c6b841705eb" xlink:href="dbx-20210331.xsd#dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsFairValue"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_4632b8ae-7a45-4939-a631-01f5f7493820" xlink:to="loc_dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsFairValue_e906bb91-7f7e-4d58-b12f-1c6b841705eb" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_32c5d67a-9987-47b9-80de-0367851d9ad1" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_4632b8ae-7a45-4939-a631-01f5f7493820" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_32c5d67a-9987-47b9-80de-0367851d9ad1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsFairValue_3832933f-64cb-4ebf-bd1f-988d883e0185" xlink:href="dbx-20210331.xsd#dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsFairValue"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDate_4632b8ae-7a45-4939-a631-01f5f7493820" xlink:to="loc_dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsFairValue_3832933f-64cb-4ebf-bd1f-988d883e0185" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_ab37f21d-0fb7-46db-8c40-9b31ba677e98" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsAmortizedCost_22e128e0-a51b-4c57-80c8-0e28f827c9f1" xlink:href="dbx-20210331.xsd#dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsAmortizedCost"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_ab37f21d-0fb7-46db-8c40-9b31ba677e98" xlink:to="loc_dbx_AvailableForSaleSecuritiesDebtMaturitiesAfterThreeYearsAmortizedCost_22e128e0-a51b-4c57-80c8-0e28f827c9f1" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost_2b2451bd-72e6-400e-bf71-e37df3337dd7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_ab37f21d-0fb7-46db-8c40-9b31ba677e98" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost_2b2451bd-72e6-400e-bf71-e37df3337dd7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsAmortizedCost_62f29310-a0e8-466c-887d-d7532d794fff" xlink:href="dbx-20210331.xsd#dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsAmortizedCost"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesSingleMaturityDateAmortizedCostBasis_ab37f21d-0fb7-46db-8c40-9b31ba677e98" xlink:to="loc_dbx_DebtSecuritiesAvailableForSaleSecuritiesMaturityAllocatedAndSingleMaturityDateAfterOneThroughThreeYearsAmortizedCost_62f29310-a0e8-466c-887d-d7532d794fff" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/FairValueMeasurements" xlink:type="simple" xlink:href="dbx-20210331.xsd#FairValueMeasurements"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/FairValueMeasurements" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/FairValueMeasurementsTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#FairValueMeasurementsTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/FairValueMeasurementsTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/FairValueMeasurementsDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#FairValueMeasurementsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/FairValueMeasurementsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_0960286f-030b-423a-980c-586fa30cfaae" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AssetsFairValueDisclosure"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_b918422f-bbc9-4691-8f9d-4170dc9cd57e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_CashAndCashEquivalentsFairValueDisclosure"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_0960286f-030b-423a-980c-586fa30cfaae" xlink:to="loc_us-gaap_CashAndCashEquivalentsFairValueDisclosure_b918422f-bbc9-4691-8f9d-4170dc9cd57e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_2fa4e882-e1f0-44ea-b1bf-906928d1cf86" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtSecurities"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_0960286f-030b-423a-980c-586fa30cfaae" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtSecurities_2fa4e882-e1f0-44ea-b1bf-906928d1cf86" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/FairValueMeasurementsNarrativeDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#FairValueMeasurementsNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/FairValueMeasurementsNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/PropertyandEquipmentNet" xlink:type="simple" xlink:href="dbx-20210331.xsd#PropertyandEquipmentNet"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/PropertyandEquipmentNet" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/PropertyandEquipmentNetTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#PropertyandEquipmentNetTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/PropertyandEquipmentNetTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/PropertyandEquipmentNetScheduleofComponentsDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#PropertyandEquipmentNetScheduleofComponentsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/PropertyandEquipmentNetScheduleofComponentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_758407eb-c2fe-4c95-8872-a61e3e9ff6ab" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_6018e571-2ebe-4343-9ac0-1dcd6c248316" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_758407eb-c2fe-4c95-8872-a61e3e9ff6ab" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_6018e571-2ebe-4343-9ac0-1dcd6c248316" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_ae43d44e-3778-400f-86a7-626c63a0b724" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentNet_758407eb-c2fe-4c95-8872-a61e3e9ff6ab" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_ae43d44e-3778-400f-86a7-626c63a0b724" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/PropertyandEquipmentNetNarrativeDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#PropertyandEquipmentNetNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/PropertyandEquipmentNetNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/BusinessCombinations" xlink:type="simple" xlink:href="dbx-20210331.xsd#BusinessCombinations"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/BusinessCombinations" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/BusinessCombinationsTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#BusinessCombinationsTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/BusinessCombinationsTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/BusinessCombinationsScheduleofPurchaseConsiderationDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#BusinessCombinationsScheduleofPurchaseConsiderationDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/BusinessCombinationsScheduleofPurchaseConsiderationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationConsiderationTransferred1_00e4368b-875a-4a09-b99b-7aedad95fd21" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationConsiderationTransferred1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherPaymentsToAcquireBusinesses_014c5c98-0b6e-4258-9598-ed05a35165ef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_OtherPaymentsToAcquireBusinesses"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationConsiderationTransferred1_00e4368b-875a-4a09-b99b-7aedad95fd21" xlink:to="loc_us-gaap_OtherPaymentsToAcquireBusinesses_014c5c98-0b6e-4258-9598-ed05a35165ef" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_BusinessCombinationConsiderationTransferredStockOptionsAssumed_15ee84bb-4a40-4117-b0cd-53118ab2f274" xlink:href="dbx-20210331.xsd#dbx_BusinessCombinationConsiderationTransferredStockOptionsAssumed"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationConsiderationTransferred1_00e4368b-875a-4a09-b99b-7aedad95fd21" xlink:to="loc_dbx_BusinessCombinationConsiderationTransferredStockOptionsAssumed_15ee84bb-4a40-4117-b0cd-53118ab2f274" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred_78ebc10a-437c-4626-a5d7-640072527bb8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationConsiderationTransferred1_00e4368b-875a-4a09-b99b-7aedad95fd21" xlink:to="loc_us-gaap_BusinessCombinationProvisionalInformationInitialAccountingIncompleteAdjustmentConsiderationTransferred_78ebc10a-437c-4626-a5d7-640072527bb8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquireBusinessesGross_5b5f97d0-71b6-4cc3-836c-d0fb2417fad9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_PaymentsToAcquireBusinessesGross"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationConsiderationTransferred1_00e4368b-875a-4a09-b99b-7aedad95fd21" xlink:to="loc_us-gaap_PaymentsToAcquireBusinessesGross_5b5f97d0-71b6-4cc3-836c-d0fb2417fad9" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/BusinessCombinationsNarrativeDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#BusinessCombinationsNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/BusinessCombinationsNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/BusinessCombinationsAssetsAcquiredandLiabilitiesAssumedDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#BusinessCombinationsAssetsAcquiredandLiabilitiesAssumedDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/BusinessCombinationsAssetsAcquiredandLiabilitiesAssumedDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_1f74ba1a-3b58-46a5-a3d5-7b58f671d24e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_1d0372f9-aa41-46ca-8264-432ffdb4d5c9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_1f74ba1a-3b58-46a5-a3d5-7b58f671d24e" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_1d0372f9-aa41-46ca-8264-432ffdb4d5c9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_6779787a-c509-4df3-806d-b3add143438e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_1f74ba1a-3b58-46a5-a3d5-7b58f671d24e" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_6779787a-c509-4df3-806d-b3add143438e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_a6212c7c-5cd7-4652-b5f1-1a53e80071a0" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_2e372b56-2167-4d57-bf46-9606ccef5a79" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_a6212c7c-5cd7-4652-b5f1-1a53e80071a0" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCashAndEquivalents_2e372b56-2167-4d57-bf46-9606ccef5a79" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_8a7cc61c-c176-435d-89d4-a7f4f6c61336" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_a6212c7c-5cd7-4652-b5f1-1a53e80071a0" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsPrepaidExpenseAndOtherAssets_8a7cc61c-c176-435d-89d4-a7f4f6c61336" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsMarketableSecurities_ae0b592a-aaed-4f1d-aa4c-8cbade240a6e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsMarketableSecurities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_a6212c7c-5cd7-4652-b5f1-1a53e80071a0" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentAssetsMarketableSecurities_ae0b592a-aaed-4f1d-aa4c-8cbade240a6e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_c7faba13-59b3-436c-8ae9-9eca5d82d900" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedAssets_a6212c7c-5cd7-4652-b5f1-1a53e80071a0" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedIntangibleAssetsOtherThanGoodwill_c7faba13-59b3-436c-8ae9-9eca5d82d900" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_6a7dfa88-55f1-4214-9b36-683c975a0089" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayable_8400b013-b121-41d2-8023-1db1ec4bc263" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayable"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_6a7dfa88-55f1-4214-9b36-683c975a0089" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesAccountsPayable_8400b013-b121-41d2-8023-1db1ec4bc263" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredRevenue_4f22a3d1-73a5-467d-8619-e8d7a5a2e006" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredRevenue"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_6a7dfa88-55f1-4214-9b36-683c975a0089" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedCurrentLiabilitiesDeferredRevenue_4f22a3d1-73a5-467d-8619-e8d7a5a2e006" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_4fc0b3dc-5590-43a5-8a03-11aa5bf8acb5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedLiabilities_6a7dfa88-55f1-4214-9b36-683c975a0089" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedDeferredTaxLiabilities_4fc0b3dc-5590-43a5-8a03-11aa5bf8acb5" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_cee04317-59c1-4946-8d58-05c6efc5f750" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Goodwill_d3f7f605-124b-4600-9f9e-068127ab2899" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_Goodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_cee04317-59c1-4946-8d58-05c6efc5f750" xlink:to="loc_us-gaap_Goodwill_d3f7f605-124b-4600-9f9e-068127ab2899" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_6d15b819-ad9b-44e6-8329-2b1f49d0ca12" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredGoodwillAndLiabilitiesAssumedNet_cee04317-59c1-4946-8d58-05c6efc5f750" xlink:to="loc_us-gaap_BusinessCombinationRecognizedIdentifiableAssetsAcquiredAndLiabilitiesAssumedNet_6d15b819-ad9b-44e6-8329-2b1f49d0ca12" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/BusinessCombinationsScheduleofAssetsAcquiredDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#BusinessCombinationsScheduleofAssetsAcquiredDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/BusinessCombinationsScheduleofAssetsAcquiredDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/IntangibleAssets" xlink:type="simple" xlink:href="dbx-20210331.xsd#IntangibleAssets"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/IntangibleAssets" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/IntangibleAssetsTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#IntangibleAssetsTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/IntangibleAssetsTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/IntangibleAssetsScheduleofIntangibleAssetsDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#IntangibleAssetsScheduleofIntangibleAssetsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/IntangibleAssetsScheduleofIntangibleAssetsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_fa554c5b-45da-45bb-ae01-3487f41537a9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_69e547a5-d721-4c14-9b7e-e386fa889e92" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IntangibleAssetsGrossExcludingGoodwill"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_fa554c5b-45da-45bb-ae01-3487f41537a9" xlink:to="loc_us-gaap_IntangibleAssetsGrossExcludingGoodwill_69e547a5-d721-4c14-9b7e-e386fa889e92" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_7a3c25eb-87bd-43fa-86c7-99b4e0b8ae9c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization"/>
    <link:calculationArc order="2" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_fa554c5b-45da-45bb-ae01-3487f41537a9" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_7a3c25eb-87bd-43fa-86c7-99b4e0b8ae9c" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/IntangibleAssetsNarrativeDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#IntangibleAssetsNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/IntangibleAssetsNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/IntangibleAssetsScheduleofFutureAmortizationExpenseDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#IntangibleAssetsScheduleofFutureAmortizationExpenseDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/IntangibleAssetsScheduleofFutureAmortizationExpenseDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_2b25f665-78a3-4020-be8c-33042d782c21" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_c70502f3-7703-4814-8a29-89cc4f820469" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_2b25f665-78a3-4020-be8c-33042d782c21" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseRemainderOfFiscalYear_c70502f3-7703-4814-8a29-89cc4f820469" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_f83c48b5-8fb2-48be-83af-9c1df78d696c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_2b25f665-78a3-4020-be8c-33042d782c21" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseNextTwelveMonths_f83c48b5-8fb2-48be-83af-9c1df78d696c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_35ead3ac-5482-41a2-b9f5-255b1fcd61d7" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_2b25f665-78a3-4020-be8c-33042d782c21" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearTwo_35ead3ac-5482-41a2-b9f5-255b1fcd61d7" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_351ac14d-5a81-44b4-8af9-8ea47b902aef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_2b25f665-78a3-4020-be8c-33042d782c21" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearThree_351ac14d-5a81-44b4-8af9-8ea47b902aef" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_97a88417-27e6-420d-a7db-e932b208f2df" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_2b25f665-78a3-4020-be8c-33042d782c21" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAmortizationExpenseYearFour_97a88417-27e6-420d-a7db-e932b208f2df" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_FiniteLivedIntangibleAssetExpectedAmortizationafterYearFour_06a302c7-49ca-487a-b203-33f8955a3be9" xlink:href="dbx-20210331.xsd#dbx_FiniteLivedIntangibleAssetExpectedAmortizationafterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_2b25f665-78a3-4020-be8c-33042d782c21" xlink:to="loc_dbx_FiniteLivedIntangibleAssetExpectedAmortizationafterYearFour_06a302c7-49ca-487a-b203-33f8955a3be9" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/Goodwill" xlink:type="simple" xlink:href="dbx-20210331.xsd#Goodwill"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/Goodwill" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/GoodwillTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#GoodwillTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/GoodwillTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/GoodwillDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#GoodwillDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/GoodwillDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/Debt" xlink:type="simple" xlink:href="dbx-20210331.xsd#Debt"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/Debt" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DebtTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#DebtTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DebtTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DebtRevolvingCreditFacilityDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DebtRevolvingCreditFacilityDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DebtRevolvingCreditFacilityDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DebtConvertibleSeniorNotesDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DebtConvertibleSeniorNotesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DebtConvertibleSeniorNotesDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/DebtScheduleofConvertibleNotesDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DebtScheduleofConvertibleNotesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DebtScheduleofConvertibleNotesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_c5a90fe4-dd0b-46f8-a497-5979c707916e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebt"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnamortizedDebtIssuanceExpense_cdb87eb6-5bf8-4ca0-92c7-91076c003936" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_UnamortizedDebtIssuanceExpense"/>
    <link:calculationArc order="1" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_c5a90fe4-dd0b-46f8-a497-5979c707916e" xlink:to="loc_us-gaap_UnamortizedDebtIssuanceExpense_cdb87eb6-5bf8-4ca0-92c7-91076c003936" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_5d7c35c9-26ad-4f7c-82a5-7d02948168d5" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LongTermDebt_c5a90fe4-dd0b-46f8-a497-5979c707916e" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_5d7c35c9-26ad-4f7c-82a5-7d02948168d5" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/DebtLongTermDebtMaturitiesDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DebtLongTermDebtMaturitiesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DebtLongTermDebtMaturitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_326b75ba-1a8c-49d4-a451-f7c2a5eb272b" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_045f51b5-a7af-4fbb-b865-816e11ede4f8" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_326b75ba-1a8c-49d4-a451-f7c2a5eb272b" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFive_045f51b5-a7af-4fbb-b865-816e11ede4f8" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_54326ded-eb5c-44e8-a453-23b01a7d5e61" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_326b75ba-1a8c-49d4-a451-f7c2a5eb272b" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearTwo_54326ded-eb5c-44e8-a453-23b01a7d5e61" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive_480540af-259f-40cd-98d2-dfa00b190eef" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_326b75ba-1a8c-49d4-a451-f7c2a5eb272b" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalAfterYearFive_480540af-259f-40cd-98d2-dfa00b190eef" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_b415478a-1417-428e-b52d-3d2f4ceed75c" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_326b75ba-1a8c-49d4-a451-f7c2a5eb272b" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInNextTwelveMonths_b415478a-1417-428e-b52d-3d2f4ceed75c" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_0ceaaff3-dc10-4ed8-a7c6-57f78c6de112" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_326b75ba-1a8c-49d4-a451-f7c2a5eb272b" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearFour_0ceaaff3-dc10-4ed8-a7c6-57f78c6de112" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_a76c4b60-26d0-4e42-9eff-2883067195dd" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_326b75ba-1a8c-49d4-a451-f7c2a5eb272b" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalRemainderOfFiscalYear_a76c4b60-26d0-4e42-9eff-2883067195dd" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_9250b4f8-0cc0-490f-9778-4bd956da5e78" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree"/>
    <link:calculationArc order="7" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DebtInstrumentCarryingAmount_326b75ba-1a8c-49d4-a451-f7c2a5eb272b" xlink:to="loc_us-gaap_LongTermDebtMaturitiesRepaymentsOfPrincipalInYearThree_9250b4f8-0cc0-490f-9778-4bd956da5e78" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/DebtConvertibleNoteHedgesandWarrantsDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#DebtConvertibleNoteHedgesandWarrantsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/DebtConvertibleNoteHedgesandWarrantsDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/Leases" xlink:type="simple" xlink:href="dbx-20210331.xsd#Leases"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/Leases" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/LeasesTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#LeasesTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/LeasesTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/LeasesNarrativeDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#LeasesNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/LeasesNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/LeasesFutureMinimumLeasePaymentsDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#LeasesFutureMinimumLeasePaymentsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/LeasesFutureMinimumLeasePaymentsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_54dc37a3-62ab-4833-9a1c-dc8329b07c39" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_922365c0-3b4d-46b2-b48e-38386435d651" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_54dc37a3-62ab-4833-9a1c-dc8329b07c39" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_922365c0-3b4d-46b2-b48e-38386435d651" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_5d8a41dd-2943-4806-ac64-299abfd541b9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_54dc37a3-62ab-4833-9a1c-dc8329b07c39" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_5d8a41dd-2943-4806-ac64-299abfd541b9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_8f59f8a9-598f-4b84-a1b7-1b4ef7bcbd78" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_54dc37a3-62ab-4833-9a1c-dc8329b07c39" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_8f59f8a9-598f-4b84-a1b7-1b4ef7bcbd78" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_83a93986-ae43-45ad-b718-6342ca011ee3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_54dc37a3-62ab-4833-9a1c-dc8329b07c39" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_83a93986-ae43-45ad-b718-6342ca011ee3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_02e52f0a-9e3c-4af6-bf56-3891c0973e54" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_54dc37a3-62ab-4833-9a1c-dc8329b07c39" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_02e52f0a-9e3c-4af6-bf56-3891c0973e54" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_LesseeOperatingLeaseLiabilitytobePaidafterYearFour_a42db494-07d2-4a00-8af2-f6069b243748" xlink:href="dbx-20210331.xsd#dbx_LesseeOperatingLeaseLiabilitytobePaidafterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_54dc37a3-62ab-4833-9a1c-dc8329b07c39" xlink:to="loc_dbx_LesseeOperatingLeaseLiabilitytobePaidafterYearFour_a42db494-07d2-4a00-8af2-f6069b243748" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_1a3f7d25-3649-4d30-91a8-fd12d818ec1e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDue"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_4afb704e-455f-435a-b2e5-3ea2e7c22c3e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_1a3f7d25-3649-4d30-91a8-fd12d818ec1e" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsRemainderOfFiscalYear_4afb704e-455f-435a-b2e5-3ea2e7c22c3e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_e874c3e9-98c6-47a9-8702-808f1867d369" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_1a3f7d25-3649-4d30-91a8-fd12d818ec1e" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueNextTwelveMonths_e874c3e9-98c6-47a9-8702-808f1867d369" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_c301bae6-4f5c-4247-a303-6ac244e69c92" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_1a3f7d25-3649-4d30-91a8-fd12d818ec1e" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearTwo_c301bae6-4f5c-4247-a303-6ac244e69c92" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_b9485ad9-7ccd-4834-9a0d-3d1de1d35dbf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_1a3f7d25-3649-4d30-91a8-fd12d818ec1e" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearThree_b9485ad9-7ccd-4834-9a0d-3d1de1d35dbf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_493d7932-0c41-482e-98e3-283b8df6b230" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_1a3f7d25-3649-4d30-91a8-fd12d818ec1e" xlink:to="loc_us-gaap_FinanceLeaseLiabilityPaymentsDueYearFour_493d7932-0c41-482e-98e3-283b8df6b230" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_FinanceLeaseLiabilitytobePaidafterYearFour_f43df935-9b29-432a-a3ad-315fce8a9a54" xlink:href="dbx-20210331.xsd#dbx_FinanceLeaseLiabilitytobePaidafterYearFour"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FinanceLeaseLiabilityPaymentsDue_1a3f7d25-3649-4d30-91a8-fd12d818ec1e" xlink:to="loc_dbx_FinanceLeaseLiabilitytobePaidafterYearFour_f43df935-9b29-432a-a3ad-315fce8a9a54" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/LeasesFutureSubtenantPaymentsReceivableDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#LeasesFutureSubtenantPaymentsReceivableDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/LeasesFutureSubtenantPaymentsReceivableDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_52743dc5-da08-417c-bf20-307f6c78118e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceived"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear_47bff0b3-43ba-43d4-b649-17c0134ba516" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_52743dc5-da08-417c-bf20-307f6c78118e" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedRemainderOfFiscalYear_47bff0b3-43ba-43d4-b649-17c0134ba516" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedFourYears_f76d8192-220d-4263-b2d4-f0bfbf2547cc" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedFourYears"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_52743dc5-da08-417c-bf20-307f6c78118e" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedFourYears_f76d8192-220d-4263-b2d4-f0bfbf2547cc" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths_c6b0fcac-1c03-4dfa-a530-9c6f374a10e4" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_52743dc5-da08-417c-bf20-307f6c78118e" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedNextTwelveMonths_c6b0fcac-1c03-4dfa-a530-9c6f374a10e4" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedTwoYears_ddbb2e8d-c007-491e-9703-22b68908abd9" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedTwoYears"/>
    <link:calculationArc order="4" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_52743dc5-da08-417c-bf20-307f6c78118e" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedTwoYears_ddbb2e8d-c007-491e-9703-22b68908abd9" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_LessorOperatingLeasePaymentsToBeReceivedAfterYearFour_12f6116b-8493-4a5c-b5a1-572bd064cc2e" xlink:href="dbx-20210331.xsd#dbx_LessorOperatingLeasePaymentsToBeReceivedAfterYearFour"/>
    <link:calculationArc order="5" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_52743dc5-da08-417c-bf20-307f6c78118e" xlink:to="loc_dbx_LessorOperatingLeasePaymentsToBeReceivedAfterYearFour_12f6116b-8493-4a5c-b5a1-572bd064cc2e" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedThreeYears_680d869e-b138-4438-8b51-cd0b4a186b66" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceivedThreeYears"/>
    <link:calculationArc order="6" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_52743dc5-da08-417c-bf20-307f6c78118e" xlink:to="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceivedThreeYears_680d869e-b138-4438-8b51-cd0b4a186b66" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/LeasesFutureSubtenantPaymentsReceivableDetails_1" xlink:type="simple" xlink:href="dbx-20210331.xsd#LeasesFutureSubtenantPaymentsReceivableDetails_1"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/LeasesFutureSubtenantPaymentsReceivableDetails_1" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_1dacc465-168d-4422-8e30-cb2bbd636b16" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_LessorOperatingLeasePaymentsToBeReceived"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_OperatingLeaseLessorOperatingLeasePaymentsToBeReceivedLessLeaseIncentives_3a5bd3de-b09c-4137-b49e-05667bb04daf" xlink:href="dbx-20210331.xsd#dbx_OperatingLeaseLessorOperatingLeasePaymentsToBeReceivedLessLeaseIncentives"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_1dacc465-168d-4422-8e30-cb2bbd636b16" xlink:to="loc_dbx_OperatingLeaseLessorOperatingLeasePaymentsToBeReceivedLessLeaseIncentives_3a5bd3de-b09c-4137-b49e-05667bb04daf" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_LessorOperatingLeaseLeaseReceivableUndiscountedExcessAmount_4dc1cffe-6871-4a0b-8966-4a9320e5ef4d" xlink:href="dbx-20210331.xsd#dbx_LessorOperatingLeaseLeaseReceivableUndiscountedExcessAmount"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LessorOperatingLeasePaymentsToBeReceived_1dacc465-168d-4422-8e30-cb2bbd636b16" xlink:to="loc_dbx_LessorOperatingLeaseLeaseReceivableUndiscountedExcessAmount_4dc1cffe-6871-4a0b-8966-4a9320e5ef4d" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/CommitmentsandContingencies" xlink:type="simple" xlink:href="dbx-20210331.xsd#CommitmentsandContingencies"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CommitmentsandContingencies" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/CommitmentsandContingenciesDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#CommitmentsandContingenciesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/CommitmentsandContingenciesDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/AccruedandOtherCurrentLiabilities" xlink:type="simple" xlink:href="dbx-20210331.xsd#AccruedandOtherCurrentLiabilities"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/AccruedandOtherCurrentLiabilities" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/AccruedandOtherCurrentLiabilitiesTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#AccruedandOtherCurrentLiabilitiesTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/AccruedandOtherCurrentLiabilitiesTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/AccruedandOtherCurrentLiabilitiesDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#AccruedandOtherCurrentLiabilitiesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/AccruedandOtherCurrentLiabilitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_f422c5e3-45ef-4952-a482-3c76c47d158f" xlink:href="dbx-20210331.xsd#dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedProfessionalFeesCurrent_5ae4c2f7-e7a6-497b-a130-17804c09b440" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccruedProfessionalFeesCurrent"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_f422c5e3-45ef-4952-a482-3c76c47d158f" xlink:to="loc_us-gaap_AccruedProfessionalFeesCurrent_5ae4c2f7-e7a6-497b-a130-17804c09b440" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_OtherAccruedLiabilitiesAndOtherLiabilitiesCurrent_1910bf9b-2ba4-46bf-b8b0-51d4cd50926a" xlink:href="dbx-20210331.xsd#dbx_OtherAccruedLiabilitiesAndOtherLiabilitiesCurrent"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_f422c5e3-45ef-4952-a482-3c76c47d158f" xlink:to="loc_dbx_OtherAccruedLiabilitiesAndOtherLiabilitiesCurrent_1910bf9b-2ba4-46bf-b8b0-51d4cd50926a" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccrualForTaxesOtherThanIncomeTaxesCurrent_b8bd0c65-63fa-49f2-a4e0-c8114002823e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_AccrualForTaxesOtherThanIncomeTaxesCurrent"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_dbx_AccruedLiabilitiesandOtherLiabilitiesCurrent_f422c5e3-45ef-4952-a482-3c76c47d158f" xlink:to="loc_us-gaap_AccrualForTaxesOtherThanIncomeTaxesCurrent_b8bd0c65-63fa-49f2-a4e0-c8114002823e" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquity" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquity"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquity" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquityTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquityTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquityTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquityCommonStockConvertiblePreferredStockPreferredStockNarrativeDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquityCommonStockConvertiblePreferredStockPreferredStockNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquityCommonStockConvertiblePreferredStockPreferredStockNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquityStockRepurchaseProgramDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquityStockRepurchaseProgramDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquityStockRepurchaseProgramDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquityEquityIncentivePlansNarrativeDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquityEquityIncentivePlansNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquityEquityIncentivePlansNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquityScheduleofStockOptionandRestrictedStockActivityDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquityScheduleofStockOptionandRestrictedStockActivityDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquityScheduleofStockOptionandRestrictedStockActivityDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquityScheduleofPreTaxIntrinsicValueDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquityScheduleofPreTaxIntrinsicValueDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquityScheduleofPreTaxIntrinsicValueDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquityAssumedStockOptionsNarrativeDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquityAssumedStockOptionsNarrativeDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquityAssumedStockOptionsNarrativeDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquityFairValueofStockOptionAssumptionsUsedDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquityFairValueofStockOptionAssumptionsUsedDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquityFairValueofStockOptionAssumptionsUsedDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/StockholdersDeficitEquityCoFounderGrantsDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#StockholdersDeficitEquityCoFounderGrantsDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/StockholdersDeficitEquityCoFounderGrantsDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/NetIncomePerShare" xlink:type="simple" xlink:href="dbx-20210331.xsd#NetIncomePerShare"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/NetIncomePerShare" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/NetIncomePerShareTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#NetIncomePerShareTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/NetIncomePerShareTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/NetIncomePerShareScheduleofEPSDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#NetIncomePerShareScheduleofEPSDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/NetIncomePerShareScheduleofEPSDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_315b6d7e-0c46-4989-85f2-12911808c49e" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_2c3c3518-36d1-48a7-b5d4-3a4efc230aad" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_NetIncomeLoss"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_315b6d7e-0c46-4989-85f2-12911808c49e" xlink:to="loc_us-gaap_NetIncomeLoss_2c3c3518-36d1-48a7-b5d4-3a4efc230aad" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DilutiveSecuritiesEffectOnBasicEarningsPerShareOther_ab241515-cf11-4670-a529-cef5e108f9d3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_DilutiveSecuritiesEffectOnBasicEarningsPerShareOther"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_315b6d7e-0c46-4989-85f2-12911808c49e" xlink:to="loc_us-gaap_DilutiveSecuritiesEffectOnBasicEarningsPerShareOther_ab241515-cf11-4670-a529-cef5e108f9d3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_DilutiveSecuritiesEffectOnBasicEPSDilutiveEffectOfReallocation_c3aaaf5d-6ec1-4096-895c-52442b9d8f47" xlink:href="dbx-20210331.xsd#dbx_DilutiveSecuritiesEffectOnBasicEPSDilutiveEffectOfReallocation"/>
    <link:calculationArc order="3" weight="-1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_315b6d7e-0c46-4989-85f2-12911808c49e" xlink:to="loc_dbx_DilutiveSecuritiesEffectOnBasicEPSDilutiveEffectOfReallocation_c3aaaf5d-6ec1-4096-895c-52442b9d8f47" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_75b076f3-bac0-47c9-818a-452491931dcf" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_09d6a30b-a62f-4f2a-a90c-43d8a8fe8ac3" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:calculationArc order="1" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_75b076f3-bac0-47c9-818a-452491931dcf" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_09d6a30b-a62f-4f2a-a90c-43d8a8fe8ac3" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_ea96c52a-6912-4273-b31e-e8de20f6b296" xlink:href="http://xbrl.fasb.org/us-gaap/2020/elts/us-gaap-2020-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements"/>
    <link:calculationArc order="2" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_75b076f3-bac0-47c9-818a-452491931dcf" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_ea96c52a-6912-4273-b31e-e8de20f6b296" xlink:type="arc"/>
    <link:loc xlink:type="locator" xlink:label="loc_dbx_IncrementalCommonSharesAttributabletoDilutiveEffectofConversionofCommonStock_a7ea950d-37d4-451f-bad2-7ae622c49b1e" xlink:href="dbx-20210331.xsd#dbx_IncrementalCommonSharesAttributabletoDilutiveEffectofConversionofCommonStock"/>
    <link:calculationArc order="3" weight="1.0" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_75b076f3-bac0-47c9-818a-452491931dcf" xlink:to="loc_dbx_IncrementalCommonSharesAttributabletoDilutiveEffectofConversionofCommonStock_a7ea950d-37d4-451f-bad2-7ae622c49b1e" xlink:type="arc"/>
  </link:calculationLink>
  <link:roleRef roleURI="http://www.dropbox.com/role/NetIncomePerShareScheduleofPotentiallyDilutiveSecuritiesExcludedfromComputationDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#NetIncomePerShareScheduleofPotentiallyDilutiveSecuritiesExcludedfromComputationDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/NetIncomePerShareScheduleofPotentiallyDilutiveSecuritiesExcludedfromComputationDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/IncomeTaxes" xlink:type="simple" xlink:href="dbx-20210331.xsd#IncomeTaxes"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/IncomeTaxes" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/IncomeTaxesDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#IncomeTaxesDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/IncomeTaxesDetails" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/GeographicAreas" xlink:type="simple" xlink:href="dbx-20210331.xsd#GeographicAreas"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/GeographicAreas" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/GeographicAreasTables" xlink:type="simple" xlink:href="dbx-20210331.xsd#GeographicAreasTables"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/GeographicAreasTables" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.dropbox.com/role/GeographicAreasDetails" xlink:type="simple" xlink:href="dbx-20210331.xsd#GeographicAreasDetails"/>
  <link:calculationLink xlink:role="http://www.dropbox.com/role/GeographicAreasDetails" xlink:type="extended"/>
</link:linkbase>
